SCHEMBL25147302

SCHEMBL25147302

c1ccc(-c2nc(-c3ccccc3)nc(-n3c4ccccc4c4cc5oc6nc(-c7ccccc7)nc(-c7ccccc7)c6c5cc43)n2)cc1

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
ATM Q13315 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
NPC1 O15118 1/20 0.34
HTT P42858 1/20 0.34
RAB9A P51151 1/20 0.34
WHR1 P49842 1/20 0.33
ADK P55263 1/20 0.32
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25146845 0.94 MEN1 (0.36) MEN1KMT2AATMSMN1; SMN2NPC1
SCHEMBL25146843 0.94 MEN1 (0.36) MEN1KMT2AATMSMN1; SMN2NPC1
SCHEMBL25147290 0.93 ALDH1A1 (0.39) MEN1KMT2AATMSMN1; SMN2NPC1
SCHEMBL25147151 0.89 ATM (0.34) MEN1KMT2AATMSMN1; SMN2NPC1
SCHEMBL25146813 0.89 MEN1 (0.33) MEN1KMT2AATMSMN1; SMN2NPC1
SCHEMBL25146832 0.89 MEN1 (0.33) MEN1KMT2AATMSMN1; SMN2NPC1
SCHEMBL25146848 0.89 ALDH1A1 (0.39) MEN1KMT2AATMSMN1; SMN2NPC1
SCHEMBL25147309 0.88
SCHEMBL25147242 0.87 SMN1; SMN2 (0.32) MEN1KMT2AATMSMN1; SMN2NPC1
SCHEMBL25147069 0.87 L3MBTL1 (0.40) MEN1KMT2AATMSMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023061998-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2023-04-20 WO disclosed