Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.53 |
| ▸ | CTSL | P07711 | 1/20 | 0.53 |
| ▸ | CTSB | P07858 | 1/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.51 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | ACE | P12821 | 3/20 | 0.50 |
| ▸ | MME | P08473 | 5/20 | 0.49 |
| ▸ | CTSK | P43235 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ECE1 | P42892 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27101824 | 0.92 | CTSS (0.53) | CTSSCTSLCTSBOPRD1OPRM1 | |
| SCHEMBL25773989 | 0.91 | CTSS (0.52) | CTSSCTSLCTSBOPRD1OPRM1 | |
| SCHEMBL18515624 | 0.89 | OPRD1 (0.53) | CTSSCTSLCTSBOPRD1OPRM1 | |
| SCHEMBL27337756 | 0.88 | CTSS (0.49) | CTSSCTSLCTSBOPRD1OPRM1 | |
| SCHEMBL18515816 | 0.88 | OPRD1 (0.57) | CTSSCTSLCTSBOPRD1OPRM1 | |
| SCHEMBL29590936 | 0.87 | OPRD1 (0.51) | CTSSCTSLCTSBOPRD1OPRM1 | |
| SCHEMBL21437346 | 0.87 | OPRD1 (0.51) | CTSSCTSLCTSBOPRD1OPRM1 | |
| SCHEMBL29714770 | 0.87 | OPRD1 (0.51) | CTSSCTSLCTSBOPRD1OPRM1 | |
| SCHEMBL30939437 | 0.87 | OPRD1 (0.51) | CTSSCTSLCTSBOPRD1OPRM1 | |
| SCHEMBL31170899 | 0.86 | OPRD1 (0.53) | CTSSCTSLCTSBOPRD1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023061405-A1 | HIGHLY-STABLE TARGETED LINKER-DRUG CONJUGATE | 成都科岭源医药技术有限公司 | 2023-04-20 | — | — | WO | disclosed |