Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 9/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | DUSP10 | Q9Y6W6 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2517366 | 0.84 | TLR7 (0.40) | TLR7 | |
| SCHEMBL2515911 | 0.82 | ABL1 (0.32) | GRM5OPRM1ABL1TLR7 | |
| SCHEMBL1774432 | 0.80 | ABL1 (0.37) | GRM5OPRM1ABL1ALDH1A1TLR7 | |
| SCHEMBL2514656 | 0.80 | ABL1 (0.35) | GRM5ABL1LMNAMAPTALDH1A1 | |
| SCHEMBL2514657 | 0.79 | HSD17B10 (0.33) | MAPTALDH1A1 | |
| SCHEMBL2511908 | 0.77 | GRM5 (0.35) | GRM5ABL1 | |
| SCHEMBL1774978 | 0.76 | TLR7 (0.34) | GRM5OPRM1ALDH1A1TLR7 | |
| SCHEMBL9979366 | 0.76 | CPB2 (0.40) | TLR7 | |
| SCHEMBL2513228 | 0.76 | CPB2 (0.40) | TLR7 | |
| SCHEMBL1775336 | 0.75 | GRM5 (0.41) | GRM5OPRM1ABL1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8034938-B2 | Imidazo[4,5-c]quinolines, 6,7,8,9-tetrahydroimidazo[4,5-c]quinolines, imidazo[4,5-c]naphthyridines, and 6,7,8,9-tetrahydroimidazo[4,5-c]naphthyridines) with a CH( R1) group in the fused ring at 1-position of imidazo ring; modulate immune response, by induction of cytokine biosynthesis or other mechanism | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-10-11 | — | — | US | disclosed |