Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 19/20 | 0.66 |
| ▸ | NQO2 | P16083 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1296899 | 0.93 | MET (0.68) | METNQO2 | |
| Hydrochloric Acid SCHEMBL1296470 | 0.93 | MET (0.68) | METNQO2 | |
| Hydrochloric Acid SCHEMBL1295618 | 0.93 | MET (0.68) | METNQO2 | |
| Hydrochloric Acid SCHEMBL17823305 | 0.89 | MET (0.65) | METNQO2 | |
| SCHEMBL2512836 | 0.88 | MET (0.73) | METNQO2 | |
| SCHEMBL3092215 | 0.86 | MET (0.71) | METNQO2 | |
| SCHEMBL2462450 | 0.85 | MET (0.82) | METNQO2 | |
| SCHEMBL30523589 | 0.85 | MET (0.82) | METNQO2 | |
| SCHEMBL18204293 | 0.82 | MET (0.54) | METNQO2 | |
| SCHEMBL30002995 | 0.82 | MET (0.70) | METNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2367815-A1 | PYRIDAZINONE DERIVATIVES | Merck Patent GmbH (DE) | 2011-09-28 | — | — | EP | disclosed |
| WO-2010072296-A1 | PYRIDAZINONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2010-07-01 | — | — | WO | disclosed |