Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 19/20 | 0.54 |
| ▸ | NQO2 | P16083 | 1/20 | 0.54 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1296899 | 0.89 | MET (0.68) | METNQO2 | |
| Hydrochloric Acid SCHEMBL1295618 | 0.88 | MET (0.68) | METNQO2 | |
| Hydrochloric Acid SCHEMBL1296470 | 0.88 | MET (0.68) | METNQO2 | |
| SCHEMBL2514985 | 0.82 | MET (0.66) | METNQO2 | |
| SCHEMBL18204292 | 0.81 | MET (0.78) | METNQO2 | |
| Hydrochloric Acid SCHEMBL17823305 | 0.80 | MET (0.65) | METNQO2 | |
| SCHEMBL29786700 | 0.79 | MET (0.52) | METNQO2 | |
| SCHEMBL2512836 | 0.78 | MET (0.73) | METNQO2 | |
| SCHEMBL3084098 | 0.77 | MET (0.62) | METNQO2 | |
| SCHEMBL3092215 | 0.77 | MET (0.71) | METNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160324855-A1 | COMBINATION OF A 6-OXO-1,6-DIHYDRO-PYRIDAZINE DERIVATIVE HAVING ANTI-CANCER ACTIVITY WITH GEFITINIB | MERCK PATENTE GMBH (DE) | 2016-11-10 | — | — | US | claimed |