Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.32 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.32 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15218207 | 0.83 | APP (0.41) | APPPIK3CBCHRNA7CACNA1GCACNA1H | |
| SCHEMBL25469510 | 0.75 | GPBAR1 (0.36) | APPPIK3CBL3MBTL1CHRNA7CACNA1G | |
| SCHEMBL12524710 | 0.73 | CHRNA7 (0.41) | APPPIK3CBCHRNA7CACNA1GCACNA1H | |
| SCHEMBL19010015 | 0.73 | CCR1 (0.45) | ALDH1A1USP2GAAPKMHPGD | |
| SCHEMBL13442743 | 0.72 | PRKCI (0.49) | PIK3CBL3MBTL1ALDH1A1USP2GAA | |
| SCHEMBL29657153 | 0.72 | PRKCI (0.49) | PIK3CBL3MBTL1ALDH1A1USP2GAA | |
| SCHEMBL24969101 | 0.71 | CHRNA7 (0.40) | APPPIK3CBL3MBTL1CHRNA7ALDH1A1 | |
| SCHEMBL46327 | 0.71 | CCR1 (0.47) | APPPIK3CBCHRNA7CACNA1GCACNA1H | |
| SCHEMBL14467508 | 0.70 | CYP1A2 (0.52) | ALDH1A1HSD17B10LMNASMN1; SMN2PIK3CA | |
| SCHEMBL21285478 | 0.70 | SRC (0.36) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11634425-B2 | Pharmaceutical compounds | PFIZER INC. (US) | 2023-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11634425-B2 | Pharmaceutical compounds | GABRA6, CHRNA6, CNR1 | APP 3387/4885PIK3CB 4766/4885L3MBTL1 1748/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.