SCHEMBL29657153

SCHEMBL29657153

CC[C@@H](C)c1ccc2c(ccn2C)c1

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PRKCI P41743 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.47
CYP2A6 P11509 1/20 0.45
CYP19A1 P11511 2/20 0.44
PKM P14618 2/20 0.41
USP2 O75604 1/20 0.41
ALDH1A1 P00352 1/20 0.41
GAA P10253 1/20 0.41
HPGD P15428 1/20 0.41
ALOX15 P16050 1/20 0.41
HSD17B10 Q99714 1/20 0.41
HSD11B1 P28845 1/20 0.38
PIK3CB P42338 1/20 0.38
POLB P06746 1/20 0.37
HDAC4 P56524 1/20 0.36
HDAC2 Q92769 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
THRB P10828 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13442743 1.00 PRKCI (0.49) PRKCIL3MBTL1CYP2A6CYP19A1PKM
SCHEMBL14867078 0.86 L3MBTL1 (0.61) PRKCIL3MBTL1CYP2A6PKMUSP2
SCHEMBL14867081 0.86 L3MBTL1 (0.61) PRKCIL3MBTL1CYP2A6PKMUSP2
SCHEMBL14867082 0.86 L3MBTL1 (0.61) PRKCIL3MBTL1CYP2A6PKMUSP2
SCHEMBL12714056 0.85 ABCB11 (0.49) PRKCIL3MBTL1CYP2A6CYP19A1PKM
SCHEMBL12714059 0.85 ABCB11 (0.49) PRKCIL3MBTL1CYP2A6CYP19A1PKM
SCHEMBL12739428 0.85 ABCB11 (0.49) PRKCIL3MBTL1CYP2A6CYP19A1PKM
SCHEMBL20353819 0.83 ALDH1A1 (0.41) L3MBTL1CYP19A1PKMUSP2ALDH1A1
SCHEMBL12714069 0.82 PRKCI (0.45) PRKCIL3MBTL1CYP2A6CYP19A1PKM
SCHEMBL12714064 0.82 PRKCI (0.45) PRKCIL3MBTL1CYP2A6CYP19A1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112851479-B Method for preparing chiral alkyl compound by catalyzing asymmetric hydrogenation reaction of olefin with iron complex catalyst 浙江大学 2022-05-13 CN disclosed