Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | SMPD3 | Q9NY59 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.37 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
| ▸ | MAT2A | P31153 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25150576 | 0.90 | SMPD3 (0.42) | SMPD3NPC1KDM5BALDH1A1MAPT | |
| SCHEMBL23013953 | 0.79 | MAOB (0.40) | MAOBSMPD3NPC1HIF1AMAT2A | |
| SCHEMBL29703795 | 0.79 | MAOB (0.40) | MAOBSMPD3NPC1HIF1AMAT2A | |
| SCHEMBL25150706 | 0.75 | DGAT1 (0.45) | NPC1ALDH1A1KDM4EGAAHPGD | |
| SCHEMBL29939181 | 0.75 | DGAT1 (0.45) | NPC1ALDH1A1KDM4EGAAHPGD | |
| SCHEMBL25150575 | 0.73 | SMPD3 (0.42) | SMPD3NPC1ALDH1A1TP53 | |
| SCHEMBL25150770 | 0.71 | KDM5B (0.39) | SMPD3PDE10AKDM5BHIF1A | |
| SCHEMBL25150557 | 0.70 | KDM5B (0.40) | MAOBNPC1KDM5BALDH1A1KDM4E | |
| SCHEMBL23014103 | 0.70 | SMPD3 (0.41) | SMPD3NPC1ALDH1A1KDM4EHPGD | |
| SCHEMBL29703828 | 0.70 | SMPD3 (0.41) | SMPD3NPC1ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11634425-B2 | Pharmaceutical compounds | PFIZER INC. (US) | 2023-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11634425-B2 | Pharmaceutical compounds | GABRA6, CHRNA6, CNR1 | MAOB 873/4885SMPD3 4665/4885NPC1 605/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.