Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.39 |
| ▸ | ATR | Q13535 | 1/20 | 0.38 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.38 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | STK4 | Q13043 | 1/20 | 0.36 |
| ▸ | STK3 | Q13188 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25150823 | 0.90 | RIPK3 (0.39) | NPC1RAB9ASMN1; SMN2PIM1ALOX15 | |
| SCHEMBL25150591 | 0.88 | RIPK3 (0.49) | NPC1RAB9ARIPK3TP53 | |
| SCHEMBL23023700 | 0.85 | SMN1; SMN2 (0.49) | NPC1RAB9ASMN1; SMN2PIM1ALOX15 | |
| SCHEMBL25150796 | 0.84 | SMN1; SMN2 (0.53) | NPC1RAB9ASMN1; SMN2PIM1ALOX15 | |
| SCHEMBL23023722 | 0.76 | DGAT1 (0.56) | NPC1RAB9ADGAT1SOAT1 | |
| SCHEMBL25150826 | 0.75 | SMN1; SMN2 (0.44) | NPC1RAB9ASMN1; SMN2PIM1ALOX15 | |
| SCHEMBL25150589 | 0.73 | RIPK3 (0.52) | NPC1RAB9ARIPK3TP53 | |
| SCHEMBL25150628 | 0.72 | MKNK1 (0.42) | SMN1; SMN2TP53 | |
| SCHEMBL25150576 | 0.71 | SMPD3 (0.42) | NPC1CNR2DGAT1SOAT1ATR | |
| SCHEMBL23023666 | 0.71 | SMN1; SMN2 (0.56) | NPC1RAB9ASMN1; SMN2PIM1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11634425-B2 | Pharmaceutical compounds | PFIZER INC. (US) | 2023-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11634425-B2 | Pharmaceutical compounds | GABRA6, CHRNA6, CNR1 | NPC1 605/4885RAB9A 1284/4885SMN1; SMN2 3427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.