Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 4/20 | 0.37 |
| ▸ | GRM5 | P41594 | 4/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 4/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.35 |
| ▸ | ATF4 | P18848 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ATR | Q13535 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | ACACA | Q13085 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30398695 | 1.00 | FPR2 (0.37) | FPR2GRM5P2RX7LCKDPP8 | |
| SCHEMBL30398820 | 0.84 | NFKB1 (0.46) | FPR2GRM5P2RX7LCKATF4 | |
| SCHEMBL25152475 | 0.84 | NFKB1 (0.46) | FPR2GRM5P2RX7LCKATF4 | |
| SCHEMBL11026824 | 0.73 | GRM5 (0.67) | FPR2GRM5P2RX7LCKDPP8 | |
| SCHEMBL10151954 | 0.73 | GRM5 (0.67) | FPR2GRM5P2RX7LCKDPP8 | |
| SCHEMBL2012099 | 0.73 | CNR1 (0.51) | MAPT | |
| SCHEMBL11034075 | 0.71 | GRM5 (0.65) | FPR2GRM5 | |
| SCHEMBL11032863 | 0.71 | GRM5 (0.65) | FPR2GRM5 | |
| SCHEMBL11029402 | 0.70 | GRM5 (0.59) | FPR2GRM5 | |
| SCHEMBL19178272 | 0.70 | GRM5 (0.59) | FPR2GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023064880-A1 | COMPOUNDS AND METHODS FOR MODULATING NUCLEIC ACID SPLICING | REMIX THERAPEUTICS INC. (US) | 2023-04-20 | — | — | WO | disclosed |