Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 13/20 | 0.51 |
| ▸ | PDPK1 | O15530 | 4/20 | 0.38 |
| ▸ | IP6K1 | Q92551 | 2/20 | 0.37 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | BCL2 | P10415 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3176187 | 0.78 | PARP1 (0.59) | PARP1PDPK1IP6K1IP6K3CA12 | |
| SCHEMBL29717535 | 0.78 | PARP1 (0.59) | PARP1PDPK1IP6K1IP6K3CA12 | |
| SCHEMBL29171979 | 0.77 | MAPT (0.36) | PARP1 | |
| SCHEMBL30013911 | 0.76 | PARP1 (0.56) | PARP1PDPK1IP6K1IP6K3CA12 | |
| SCHEMBL18954101 | 0.76 | PARP1 (0.56) | PARP1PDPK1IP6K1IP6K3CA12 | |
| SCHEMBL2798284 | 0.72 | PARP1 (0.51) | PARP1PDPK1IP6K1SMN1; SMN2ALDH1A1 | |
| SCHEMBL30988805 | 0.72 | PARP1 (0.51) | PARP1PDPK1IP6K1SMN1; SMN2ALDH1A1 | |
| SCHEMBL27159699 | 0.71 | ALDH1A1 (0.32) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL8210731 | 0.71 | PARP1 (0.58) | PARP1PDPK1IP6K1CA12ALOX15 | |
| SCHEMBL27160201 | 0.70 | ENPP2 (0.41) | PARP1CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023064880-A1 | COMPOUNDS AND METHODS FOR MODULATING NUCLEIC ACID SPLICING | REMIX THERAPEUTICS INC. (US) | 2023-04-20 | — | — | WO | disclosed |