Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGAV | P06756 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.32 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.32 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GABRP | O00591 | 2/20 | 0.31 |
| ▸ | GABRD | O14764 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25152079 | 0.84 | HCAR2 (0.43) | HCAR2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL19003676 | 0.80 | PSEN1 (0.38) | HCAR2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL10205366 | 0.80 | HCAR2 (0.36) | HCAR2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL11613186 | 0.70 | HCAR2 (0.38) | HCAR2SLC6A3P2RX7 | |
| SCHEMBL23489973 | 0.68 | PSEN1 (0.34) | HCAR2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL18948474 | 0.68 | NR1I2 (0.33) | HCAR2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL22758634 | 0.68 | NR1I2 (0.33) | HCAR2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL11568943 | 0.67 | HCAR2 (0.48) | HCAR2SLC6A3ALDH1A1 | |
| SCHEMBL25152946 | 0.67 | HCAR2 (0.41) | HCAR2ITGB3ITGAVITGA2BP2RX7 | |
| SCHEMBL5119804 | 0.66 | PSEN1 (0.37) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11634396-B2 | Opioid receptor modulators | EPIODYNE, INC. (US) | 2023-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11634396-B2 | Opioid receptor modulators | OPRM1, OPRK1, OPRL1 | HCAR2 200/4885PSEN1 4289/4885PSEN2 4164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.