Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.48 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 4/20 | 0.41 |
| ▸ | MMP3 | P08254 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | CPA1 | P15085 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3299318 | 1.00 | MAPT (0.51) | MAPTGABBR2GABBR1CYP2C19ATM | |
| SCHEMBL25152388 | 1.00 | MAPT (0.51) | MAPTGABBR2GABBR1CYP2C19ATM | |
| SCHEMBL9468344 | 0.89 | MAPT (0.49) | MAPTGABBR2GABBR1CYP2C19L3MBTL1 | |
| SCHEMBL9692678 | 0.85 | MAPT (0.41) | MAPTGABBR2GABBR1CYP2C19ATM | |
| SCHEMBL3355077 | 0.85 | CYP2C9 (0.45) | MAPTCYP2C19FFAR1SLC6A2SLC6A3 | |
| SCHEMBL26621253 | 0.85 | CYP2C9 (0.45) | MAPTCYP2C19FFAR1SLC6A2SLC6A3 | |
| SCHEMBL364044 | 0.83 | CYP1A2 (0.42) | MAPTCYP2C19FFAR1 | |
| SCHEMBL29185565 | 0.83 | HIF1A (0.47) | MAPTHIF1ASLC6A3 | |
| SCHEMBL15557927 | 0.82 | MAPT (0.46) | MAPTGABBR2GABBR1CYP2C19FFAR1 | |
| SCHEMBL10506506 | 0.82 | MAPT (0.40) | MAPTGABBR2GABBR1ATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11634396-B2 | Opioid receptor modulators | EPIODYNE, INC. (US) | 2023-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11634396-B2 | Opioid receptor modulators | OPRM1, OPRK1, OPRL1 | MAPT 1254/4885GABBR2 343/4885GABBR1 397/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.