Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 12/20 | 0.57 |
| ▸ | OPRD1 | P41143 | 11/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25152778 | 0.84 | PLA2G10 (0.50) | OPRK1OPRD1OPRM1MEN1KMT2A | |
| SCHEMBL6318879 | 0.78 | OPRK1 (0.56) | OPRK1OPRD1OPRM1ALDH1A1LMNA | |
| SCHEMBL27487738 | 0.78 | OPRK1 (0.56) | OPRK1OPRD1OPRM1ALDH1A1LMNA | |
| SCHEMBL16709791 | 0.76 | PLA2G10 (0.69) | OPRK1OPRD1OPRM1PLA2G10PLA2G2A | |
| SCHEMBL25152370 | 0.73 | OPRM1 (0.67) | OPRK1OPRD1OPRM1ALDH1A1LMNA | |
| SCHEMBL23405295 | 0.72 | OPRM1 (0.77) | OPRK1OPRD1OPRM1 | |
| SCHEMBL28569460 | 0.72 | OPRM1 (0.54) | OPRK1OPRD1OPRM1ALDH1A1LMNA | |
| SCHEMBL28569463 | 0.72 | OPRM1 (0.54) | OPRK1OPRD1OPRM1ALDH1A1LMNA | |
| SCHEMBL271176 | 0.72 | ATM (0.51) | OPRK1OPRD1OPRM1ALDH1A1LMNA | |
| SCHEMBL18232484 | 0.72 | OPRM1 (0.56) | OPRK1OPRD1OPRM1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11634396-B2 | Opioid receptor modulators | EPIODYNE, INC. (US) | 2023-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11634396-B2 | Opioid receptor modulators | OPRM1, OPRK1, OPRL1 | OPRK1 2/4885OPRD1 4/4885OPRM1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.