Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 13/20 | 0.76 |
| ▸ | HTR2A | P28223 | 11/20 | 0.76 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 2/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8959657 | 0.86 | HTR2C (0.71) | HTR2CHTR2APRMT5HTR7P2RX7 | |
| SCHEMBL8959650 | 0.86 | HTR2C (0.71) | HTR2CHTR2APRMT5HTR7P2RX7 | |
| SCHEMBL9230485 | 0.86 | HTR2C (1.00) | HTR2CHTR2APRMT5HTR7CYP1A2 | |
| SCHEMBL9230483 | 0.86 | HTR2C (1.00) | HTR2CHTR2APRMT5HTR7CYP1A2 | |
| SCHEMBL13283050 | 0.86 | HTR2C (0.76) | HTR2CHTR2APRMT5CYP1A2CYP3A4 | |
| SCHEMBL26673242 | 0.81 | HTR2C (0.77) | HTR2CHTR2AHTR7P2RX7CYP1A2 | |
| SCHEMBL24144837 | 0.81 | HTR2C (0.58) | HTR2CHTR2APRMT5HTR7CYP1A2 | |
| SCHEMBL26674331 | 0.81 | HTR7 (0.53) | HTR2CHTR2AHTR7CYP1A2CYP3A4 | |
| SCHEMBL24142902 | 0.81 | HTR7 (0.63) | HTR2CHTR2APRMT5HTR7 | |
| SCHEMBL15712674 | 0.81 | HTR2C (0.55) | HTR2CHTR2AHTR7CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023064345-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | VANQUA BIO, INC. (US) | 2023-04-20 | — | — | WO | disclosed |