Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.45 |
| ▸ | ACACB | O00763 | 2/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25154182 | 1.00 | GPR119 (0.53) | GPR119HRH3SYKHDAC1HDAC2 | |
| SCHEMBL30478584 | 0.85 | FFAR4 (0.51) | HRH3KDM4EALDH1A1MAPTACACB | |
| SCHEMBL26127089 | 0.82 | HRH3 (0.60) | GPR119HRH3SYKKDM4EALDH1A1 | |
| SCHEMBL15282654 | 0.81 | HRH3 (0.48) | GPR119HRH3HDAC1MAPTUSP30 | |
| SCHEMBL17793695 | 0.79 | HRH3 (0.46) | GPR119HRH3SYKMAPTUSP30 | |
| SCHEMBL30478511 | 0.78 | GPR119 (0.50) | GPR119HDAC1HDAC2ACACB | |
| SCHEMBL30327670 | 0.78 | FFAR4 (0.59) | GPR119HRH3SYKKDM4EALDH1A1 | |
| SCHEMBL30327813 | 0.78 | FFAR4 (0.45) | GPR119HRH3SYKKDM4EALDH1A1 | |
| SCHEMBL25154253 | 0.78 | GPR119 (0.54) | GPR119HDAC1HDAC2USP30HCRTR1 | |
| SCHEMBL30478566 | 0.78 | GPR119 (0.49) | GPR119ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023064345-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | VANQUA BIO, INC. (US) | 2023-04-20 | — | — | WO | disclosed |