Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.44 |
| ▸ | SYK | P43405 | 2/20 | 0.44 |
| ▸ | RET | P07949 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 3/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 2/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17793706 | 0.83 | STS (0.43) | GPR119SYKRETTACR1ACACB | |
| SCHEMBL17793699 | 0.82 | RET (0.44) | GPR119SYKRETTACR1STS | |
| SCHEMBL15282654 | 0.82 | HRH3 (0.48) | HRH3GPR119RETFFAR4USP30 | |
| SCHEMBL17793703 | 0.81 | IRAK4 (0.49) | HRH3GPR119RETUSP30 | |
| SCHEMBL31254496 | 0.80 | GPR119 (0.62) | GPR119RETUSP30 | |
| SCHEMBL26127089 | 0.79 | HRH3 (0.60) | HRH3GPR119SYKFFAR4MAPT | |
| SCHEMBL24962301 | 0.79 | GPR119 (0.57) | GPR119RETTACR1STSRORC | |
| SCHEMBL3788239 | 0.79 | MAP3K12 (0.47) | HRH3GPR119SYKTACR1STS | |
| SCHEMBL25154184 | 0.79 | GPR119 (0.53) | HRH3GPR119SYKFFAR4USP30 | |
| SCHEMBL25154182 | 0.79 | GPR119 (0.53) | HRH3GPR119SYKFFAR4USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016084866-A1 | NOVEL DIAZABICYCLO DERIVATIVE | 持田製薬株式会社 | 2016-06-02 | — | — | WO | disclosed |