Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.37 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.37 |
| ▸ | ITGAV | P06756 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.37 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.37 |
| ▸ | ITGAL | P20701 | 1/20 | 0.37 |
| ▸ | SLC6A1 | P30531 | 4/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.36 |
| ▸ | SLC6A12 | P48065 | 4/20 | 0.36 |
| ▸ | SLC6A11 | P48066 | 4/20 | 0.36 |
| ▸ | SLC6A13 | Q9NSD5 | 3/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.36 |
| ▸ | GABRR1 | P24046 | 3/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2915698 | 1.00 | TSHR (0.40) | TSHRITGB3ITGB2ITGB1ITGAV | |
| SCHEMBL2914157 | 0.89 | TSHR (0.38) | TSHRITGB3ITGB2ITGB1ITGAV | |
| SCHEMBL2918458 | 0.84 | BIRC2 (0.32) | BIRC2 | |
| SCHEMBL2912146 | 0.84 | TSHR (0.39) | TSHRITGB3ITGB2ITGB1ITGAV | |
| SCHEMBL24721279 | 0.84 | BIRC2 (0.32) | BIRC2 | |
| SCHEMBL2917177 | 0.81 | REN (0.35) | GRIN2DGRIN3BTHRBGRIN1GRIN2A | |
| SCHEMBL2917590 | 0.81 | DPP4 (0.34) | TSHRBIRC2 | |
| SCHEMBL2921471 | 0.81 | BRD4 (0.44) | — | |
| SCHEMBL2919417 | 0.78 | POLB (0.39) | TSHRCYP1A2CYP2C19LMNAMAPT | |
| SCHEMBL24952530 | 0.77 | CCR2 (0.41) | TSHRITGB3ITGB2ITGB1ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024123999-A1 | TREATMENT OF GRAFT-VERSUS-HOST DISEASE WITH INHIBITORS OF BET FAMILY BDII BROMODOMAIN | POSEIDON INNOVATION 1, INC. (US) | 2024-06-13 | — | — | WO | disclosed |
| WO-2023064768-A1 | G-PROTEIN-COUPLED RECEPTOR REGULATORS AND METHODS OF USE THEREOF | BAYLOR COLLEGE OF MEDICINE (US) | 2023-04-20 | — | — | WO | disclosed |