SCHEMBL251545

SCHEMBL251545

c1ccc(-c2cc(-c3cccnc3)c(-c3ccccc3)c3c2-c2cccc4cccc-3c24)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 5/20 0.48
CYP11B2 P19099 4/20 0.46
TNF P01375 1/20 0.45
KMO O15229 1/20 0.43
GPR84 Q9NQS5 1/20 0.43
CYP19A1 P11511 3/20 0.43
PDK2 Q15119 2/20 0.43
CYP17A1 P05093 1/20 0.43
MAPT P10636 3/20 0.43
ALDH1A1 P00352 3/20 0.43
POLB P06746 1/20 0.43
TSHR P16473 1/20 0.43
GAA P10253 2/20 0.40
PTGS2 P35354 1/20 0.40
MAPK1 P28482 1/20 0.40
HTT P42858 1/20 0.40
HSD17B10 Q99714 1/20 0.40
KDM4E B2RXH2 2/20 0.40
CYP2A6 P11509 2/20 0.40
HPGD P15428 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2734079 0.99 CYP11B1 (0.49) CYP11B1CYP11B2TNFKMOGPR84
SCHEMBL16658470 0.94 CYP11B1 (0.48) CYP11B1CYP11B2TNFKMOGPR84
SCHEMBL16658475 0.93 CYP11B1 (0.43) CYP11B1CYP11B2TNFKMOGPR84
SCHEMBL16658473 0.93 CYP11B1 (0.47) CYP11B1CYP11B2TNFKMOGPR84
SCHEMBL2734539 0.91 CYP11B1 (0.49) CYP11B1CYP11B2TNFKMOGPR84
SCHEMBL2734074 0.91 CYP19A1 (0.44) CYP11B1CYP11B2TNFKMOGPR84
SCHEMBL2734065 0.88 ATM (0.43) CYP11B1CYP11B2TNFPDK2ALDH1A1
SCHEMBL2734566 0.87 TNF (0.45) TNFMAPTALDH1A1TSHRMAPK1
SCHEMBL2733773 0.87 CYP11B1 (0.41) CYP11B1CYP11B2KMOGPR84CYP19A1
SCHEMBL2733775 0.87 CYP11B1 (0.51) CYP11B1CYP11B2TNFGPR84CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8088500-B2 OLED device with fluoranthene electron injection materials GLOBAL OLED TECHNOLOGY LLC (US) 2012-01-03 US disclosed
US-8088500-B2 OLED device with fluoranthene electron injection materials GLOBAL OLED TECHNOLOGY LLC (US) 2012-01-03 US disclosed
US-8088500-B2 OLED device with fluoranthene electron injection materials GLOBAL OLED TECHNOLOGY LLC (US) 2012-01-03 US disclosed
WO-2010114838-A1 OLED DEVICE CONTAINING A SILYL-FLUORANTHENE DERIVATIVE GLOBAL OLED TECHNOLOGY LLC (US) 2010-10-07 WO disclosed
US-20100244677-A1 OLED DEVICE CONTAINING A SILYL-FLUORANTHENE DERIVATIVE GLOBAL OLED TECHNOLOGY LLC 2010-09-30 US disclosed
US-20100244677-A1 OLED DEVICE CONTAINING A SILYL-FLUORANTHENE DERIVATIVE GLOBAL OLED TECHNOLOGY LLC 2010-09-30 US disclosed
US-20100117520-A1 OLED DEVICE WITH FLUORANTHENE ELECTRON INJECTION MATERIALS GLOBAL OLED TECHNOLOGY LLC 2010-05-13 US disclosed
US-20100117520-A1 OLED DEVICE WITH FLUORANTHENE ELECTRON INJECTION MATERIALS GLOBAL OLED TECHNOLOGY LLC 2010-05-13 US disclosed
US-20100117520-A1 OLED DEVICE WITH FLUORANTHENE ELECTRON INJECTION MATERIALS GLOBAL OLED TECHNOLOGY LLC 2010-05-13 US disclosed