SCHEMBL2734065

SCHEMBL2734065

c1ccc(-c2cc(-c3cncnc3)c(-c3ccccc3)c3c2-c2cccc4cccc-3c24)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.43
TNF P01375 1/20 0.41
PDK2 Q15119 7/20 0.40
CYP1B1 Q16678 1/20 0.38
ALDH1A1 P00352 2/20 0.38
TSHR P16473 2/20 0.38
MAPK1 P28482 2/20 0.38
HSD17B10 Q99714 2/20 0.38
TP53 P04637 1/20 0.38
HPGD P15428 1/20 0.38
CASP1 P29466 1/20 0.38
CASP7 P55210 1/20 0.38
HIF1A Q16665 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.37
JAK2 O60674 1/20 0.36
LCK P06239 1/20 0.36
LYN P07948 1/20 0.36
KCNA5 P22460 1/20 0.36
CDK2 P24941 1/20 0.36
TYK2 P29597 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16677124 0.92 ATM (0.42) ATMTNFPDK2CYP1B1ALDH1A1
SCHEMBL16670079 0.92 ATM (0.42) ATMTNFPDK2CYP1B1ALDH1A1
SCHEMBL2158220 0.89 ALDH1A1 (0.47) ATMTNFALDH1A1TSHRMAPK1
SCHEMBL251545 0.88 CYP11B1 (0.48) TNFPDK2ALDH1A1TSHRMAPK1
SCHEMBL16677154 0.87 ATM (0.38) ATMPDK2CYP1B1ALDH1A1TSHR
SCHEMBL2734079 0.87 CYP11B1 (0.49) TNFPDK2ALDH1A1TSHRMAPK1
SCHEMBL2734566 0.86 TNF (0.45) ATMTNFALDH1A1TSHRMAPK1
SCHEMBL16658470 0.86 CYP11B1 (0.48) TNFPDK2ALDH1A1TSHRMAPK1
SCHEMBL16859291 0.85 ALDH1A1 (0.44) ATMTNFALDH1A1TSHRMAPK1
SCHEMBL76389 0.85 ALDH1A1 (0.44) ATMTNFALDH1A1TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8088500-B2 OLED device with fluoranthene electron injection materials GLOBAL OLED TECHNOLOGY LLC (US) 2012-01-03 US disclosed
US-8088500-B2 OLED device with fluoranthene electron injection materials GLOBAL OLED TECHNOLOGY LLC (US) 2012-01-03 US disclosed
WO-2010114838-A1 OLED DEVICE CONTAINING A SILYL-FLUORANTHENE DERIVATIVE GLOBAL OLED TECHNOLOGY LLC (US) 2010-10-07 WO disclosed
US-20100244677-A1 OLED DEVICE CONTAINING A SILYL-FLUORANTHENE DERIVATIVE GLOBAL OLED TECHNOLOGY LLC 2010-09-30 US disclosed
US-20100244677-A1 OLED DEVICE CONTAINING A SILYL-FLUORANTHENE DERIVATIVE GLOBAL OLED TECHNOLOGY LLC 2010-09-30 US disclosed
US-20100117520-A1 OLED DEVICE WITH FLUORANTHENE ELECTRON INJECTION MATERIALS GLOBAL OLED TECHNOLOGY LLC 2010-05-13 US disclosed
US-20100117520-A1 OLED DEVICE WITH FLUORANTHENE ELECTRON INJECTION MATERIALS GLOBAL OLED TECHNOLOGY LLC 2010-05-13 US disclosed