SCHEMBL2734539

SCHEMBL2734539

c1ccc(-c2c(-c3cccnc3)cc(-c3cccc4ccccc34)c3c2-c2cccc4cccc-3c24)cc1

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 8/20 0.49
KDM4E B2RXH2 1/20 0.47
ALDH1A1 P00352 1/20 0.47
MAPT P10636 1/20 0.47
HPGD P15428 1/20 0.47
RAB9A P51151 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
GPR84 Q9NQS5 1/20 0.44
TNF P01375 1/20 0.43
CYP11B2 P19099 7/20 0.41
CYP2C9 P11712 2/20 0.40
PDK2 Q15119 2/20 0.39
KMO O15229 1/20 0.39
BCHE P06276 1/20 0.39
CYP17A1 P05093 3/20 0.38
CYP19A1 P11511 2/20 0.38
DHPS P49366 1/20 0.38
SLC22A12 Q96S37 1/20 0.38
CYP3A4 P08684 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2734542 0.95 CYP11B1 (0.51) CYP11B1KDM4EALDH1A1MAPTHPGD
SCHEMBL2734079 0.92 CYP11B1 (0.49) CYP11B1KDM4EALDH1A1MAPTHPGD
SCHEMBL251545 0.91 CYP11B1 (0.48) CYP11B1KDM4EALDH1A1MAPTHPGD
SCHEMBL2733775 0.88 CYP11B1 (0.51) CYP11B1KDM4EALDH1A1MAPTHPGD
SCHEMBL2140937 0.87 ALDH1A1 (0.40) KDM4EALDH1A1MAPTHPGDSMN1; SMN2
SCHEMBL16658470 0.86 CYP11B1 (0.48) CYP11B1KDM4EALDH1A1MAPTHPGD
SCHEMBL16658473 0.85 CYP11B1 (0.47) CYP11B1KDM4EALDH1A1MAPTHPGD
SCHEMBL16658475 0.85 CYP11B1 (0.43) CYP11B1KDM4EALDH1A1MAPTHPGD
SCHEMBL13146171 0.83 CYP11B1 (0.59) CYP11B1KDM4EALDH1A1MAPTHPGD
SCHEMBL2734074 0.82 CYP19A1 (0.44) CYP11B1KDM4EALDH1A1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8088500-B2 OLED device with fluoranthene electron injection materials GLOBAL OLED TECHNOLOGY LLC (US) 2012-01-03 US disclosed
US-8088500-B2 OLED device with fluoranthene electron injection materials GLOBAL OLED TECHNOLOGY LLC (US) 2012-01-03 US disclosed
US-20100117520-A1 OLED DEVICE WITH FLUORANTHENE ELECTRON INJECTION MATERIALS GLOBAL OLED TECHNOLOGY LLC 2010-05-13 US disclosed
US-20100117520-A1 OLED DEVICE WITH FLUORANTHENE ELECTRON INJECTION MATERIALS GLOBAL OLED TECHNOLOGY LLC 2010-05-13 US disclosed