Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.35 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.34 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.34 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25154774 | 1.00 | HTR2C (0.40) | HTR2CCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL25154420 | 1.00 | HTR2C (0.40) | HTR2CCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL18081172 | 0.79 | CHRNB2 (0.46) | HTR2CCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL377976 | 0.79 | CHRNB2 (0.46) | HTR2CCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL1481267 | 0.79 | CHRNB2 (0.46) | HTR2CCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL25154422 | 0.79 | SLC6A1 (0.36) | HTR2CCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL25154781 | 0.79 | SLC6A1 (0.36) | HTR2CCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL25154658 | 0.79 | SLC6A1 (0.36) | HTR2CCHRNB2CHRNB4CHRNA3CHRNA4 | |
| Hydrochloric Acid SCHEMBL15956717 | 0.77 | CHRNB2 (0.45) | HTR2CCHRNB2CHRNB4CHRNA3CHRNA4 | |
| Hydrochloric Acid SCHEMBL1480990 | 0.77 | CHRNB2 (0.45) | HTR2CCHRNB2CHRNB4CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023064768-A1 | G-PROTEIN-COUPLED RECEPTOR REGULATORS AND METHODS OF USE THEREOF | BAYLOR COLLEGE OF MEDICINE (US) | 2023-04-20 | — | — | WO | disclosed |