Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HPN | P05981 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | SPR | P35270 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25155486 | 0.89 | SMN1; SMN2 (0.46) | SMN1; SMN2CACNA1HCACNA1BCACNA1CKDM4A | |
| SCHEMBL31359957 | 0.88 | BCHE (0.42) | BCHECYP1A2KDM4EHSD17B10 | |
| SCHEMBL25155255 | 0.80 | NPC1 (0.38) | SMN1; SMN2KDM4ARAB9ANPC1BCHE | |
| SCHEMBL25155380 | 0.79 | CACNA1H (0.51) | SMN1; SMN2CACNA1HCACNA1BCACNA1CKDM4A | |
| SCHEMBL31360370 | 0.79 | CACNA1H (0.51) | SMN1; SMN2CACNA1HCACNA1BCACNA1CKDM4A | |
| SCHEMBL31359829 | 0.79 | NPC1 (0.43) | SMN1; SMN2KDM4ARAB9ANPC1CYP1A2 | |
| SCHEMBL30344772 | 0.79 | NPC1 (0.43) | SMN1; SMN2KDM4ARAB9ANPC1CYP1A2 | |
| SCHEMBL25156527 | 0.79 | NPC1 (0.43) | SMN1; SMN2KDM4ARAB9ANPC1CYP1A2 | |
| SCHEMBL25156122 | 0.78 | MTNR1A (0.43) | SMN1; SMN2BCHECYP1A2KDM4EHSD17B10 | |
| SCHEMBL25156361 | 0.78 | HDAC1 (0.40) | SMN1; SMN2KDM4ARAB9ANPC1HPN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250025443-A1 | COMPOUNDS AND METHODS FOR TREATING CORONA VIRUSES | Clear Creek Bio, Inc. (US) | 2025-01-23 | — | — | US | disclosed |
| WO-2023064493-A1 | COMPOUNDS AND METHODS FOR TREATING CORONAVIRUSES | Clear Creek Bio, Inc. (US) | 2023-04-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250025443-A1 | COMPOUNDS AND METHODS FOR TREATING CORONA VIRUSES | ACE, PREP, PEPD | SMN1; SMN2 4601/4885CACNA1H 1528/4885CACNA1B 1177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.