Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 5/20 | 0.35 |
| ▸ | ACACA | Q13085 | 3/20 | 0.35 |
| ▸ | TACR3 | P29371 | 1/20 | 0.34 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.34 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.34 |
| ▸ | KLK1 | P06870 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25156361 | 0.95 | HDAC1 (0.40) | NPC1RAB9APDE2ASMN1; SMN2KDM4A | |
| SCHEMBL31359852 | 0.91 | PDE2A (0.37) | NPC1RAB9APDE2ASMN1; SMN2KDM4A | |
| SCHEMBL31360418 | 0.91 | SMN1; SMN2 (0.35) | NPC1RAB9APDE2ASMN1; SMN2KDM4A | |
| SCHEMBL25155551 | 0.91 | PDE2A (0.37) | NPC1RAB9APDE2ASMN1; SMN2KDM4A | |
| SCHEMBL25155396 | 0.91 | SMN1; SMN2 (0.35) | NPC1RAB9APDE2ASMN1; SMN2KDM4A | |
| SCHEMBL31359947 | 0.87 | KDM4A (0.36) | NPC1RAB9ASMN1; SMN2KDM4AHDAC1 | |
| SCHEMBL25156056 | 0.87 | KDM4A (0.36) | NPC1RAB9ASMN1; SMN2KDM4AHDAC1 | |
| SCHEMBL25155152 | 0.82 | KLKB1 (0.43) | NPC1RAB9APDE2ASLC6A9TACR3 | |
| SCHEMBL25155252 | 0.80 | SMN1; SMN2 (0.44) | NPC1RAB9ASMN1; SMN2KDM4AHDAC1 | |
| SCHEMBL25155772 | 0.79 | NQO2 (0.41) | BCHEACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250025443-A1 | COMPOUNDS AND METHODS FOR TREATING CORONA VIRUSES | Clear Creek Bio, Inc. (US) | 2025-01-23 | — | — | US | disclosed |
| WO-2023064493-A1 | COMPOUNDS AND METHODS FOR TREATING CORONAVIRUSES | Clear Creek Bio, Inc. (US) | 2023-04-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250025443-A1 | COMPOUNDS AND METHODS FOR TREATING CORONA VIRUSES | ACE, PREP, PEPD | NPC1 1002/4885RAB9A 3136/4885PDE2A 1481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.