Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25156016 | 0.87 | CYP1A2 (0.49) | ALDH1A1KDM4ESMN1; SMN2CYP1A2CYP2D6 | |
| SCHEMBL25155521 | 0.86 | HRH3 (0.45) | ALDH1A1KDM4ESMN1; SMN2HTR7CYP1A2 | |
| SCHEMBL25383828 | 0.78 | HTR7 (0.54) | ALDH1A1KDM4ESMN1; SMN2HTR7TSHR | |
| SCHEMBL25427117 | 0.77 | ALDH1A1 (0.55) | ALDH1A1KDM4ESMN1; SMN2CYP1A2CYP2D6 | |
| SCHEMBL27040855 | 0.77 | KDM4E (0.58) | ALDH1A1KDM4ESMN1; SMN2HTR7CYP1A2 | |
| SCHEMBL31492990 | 0.75 | KDM4E (0.45) | ALDH1A1KDM4ESMN1; SMN2HTR7TDP1 | |
| SCHEMBL23861156 | 0.75 | KDM4E (0.55) | ALDH1A1KDM4ESMN1; SMN2HTR7CYP1A2 | |
| SCHEMBL25331400 | 0.75 | LCK (0.65) | ALDH1A1KDM4ECYP1A2CYP2D6CYP2C19 | |
| SCHEMBL1974546 | 0.75 | KDM4E (0.44) | ALDH1A1KDM4ESMN1; SMN2HTR7CYP1A2 | |
| SCHEMBL25155204 | 0.74 | KDM4E (0.57) | ALDH1A1KDM4ETDP1HRH3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023064493-A1 | COMPOUNDS AND METHODS FOR TREATING CORONAVIRUSES | Clear Creek Bio, Inc. (US) | 2023-04-20 | — | — | WO | disclosed |