Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 4/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | FPR3 | P25089 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
| ▸ | HPN | P05981 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31360418 | 1.00 | SMN1; SMN2 (0.35) | SMN1; SMN2IDO1RAB9ANPC1PDE2A | |
| SCHEMBL25155255 | 0.91 | NPC1 (0.38) | SMN1; SMN2RAB9ANPC1PDE2AKDM4A | |
| SCHEMBL31359852 | 0.88 | PDE2A (0.37) | SMN1; SMN2RAB9ANPC1PDE2AKDM4A | |
| SCHEMBL25155551 | 0.88 | PDE2A (0.37) | SMN1; SMN2RAB9ANPC1PDE2AKDM4A | |
| SCHEMBL25156361 | 0.87 | HDAC1 (0.40) | SMN1; SMN2RAB9ANPC1PDE2AKDM4A | |
| SCHEMBL31359947 | 0.84 | KDM4A (0.36) | SMN1; SMN2RAB9ANPC1KDM4AHPN | |
| SCHEMBL25156056 | 0.84 | KDM4A (0.36) | SMN1; SMN2RAB9ANPC1KDM4AHPN | |
| SCHEMBL31359826 | 0.84 | IDO1 (0.39) | SMN1; SMN2IDO1PDE2A | |
| SCHEMBL25155354 | 0.84 | IDO1 (0.39) | SMN1; SMN2IDO1PDE2A | |
| SCHEMBL25155772 | 0.76 | NQO2 (0.41) | MAPTBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023064493-A1 | COMPOUNDS AND METHODS FOR TREATING CORONAVIRUSES | Clear Creek Bio, Inc. (US) | 2023-04-20 | — | — | WO | disclosed |
| WO-2023064493-A1 | COMPOUNDS AND METHODS FOR TREATING CORONAVIRUSES | Clear Creek Bio, Inc. (US) | 2023-04-20 | — | — | WO | disclosed |