SCHEMBL31360418

SCHEMBL31360418

Cc1cc2cc(CNC(=O)OC(C)(C)C)[nH]c2cc1C(=O)NC1(c2cccc(Br)c2)CC1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.35
IDO1 P14902 1/20 0.35
RAB9A P51151 2/20 0.34
NPC1 O15118 1/20 0.34
PDE2A O00408 4/20 0.34
KDM4A O75164 1/20 0.33
CTSB P07858 1/20 0.32
CTSS P25774 1/20 0.32
CTSK P43235 1/20 0.32
FPR3 P25089 1/20 0.32
FPR2 P25090 1/20 0.32
AAK1 Q2M2I8 1/20 0.32
HPN P05981 1/20 0.32
LCK P06239 1/20 0.31
MEN1 O00255 1/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
KMT2A Q03164 1/20 0.31
CYP1A2 P05177 1/20 0.31
CACNA1H O95180 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25155396 1.00 SMN1; SMN2 (0.35) SMN1; SMN2IDO1RAB9ANPC1PDE2A
SCHEMBL25155255 0.91 NPC1 (0.38) SMN1; SMN2RAB9ANPC1PDE2AKDM4A
SCHEMBL31359852 0.88 PDE2A (0.37) SMN1; SMN2RAB9ANPC1PDE2AKDM4A
SCHEMBL25155551 0.88 PDE2A (0.37) SMN1; SMN2RAB9ANPC1PDE2AKDM4A
SCHEMBL25156361 0.87 HDAC1 (0.40) SMN1; SMN2RAB9ANPC1PDE2AKDM4A
SCHEMBL31359947 0.84 KDM4A (0.36) SMN1; SMN2RAB9ANPC1KDM4AHPN
SCHEMBL25156056 0.84 KDM4A (0.36) SMN1; SMN2RAB9ANPC1KDM4AHPN
SCHEMBL31359826 0.84 IDO1 (0.39) SMN1; SMN2IDO1PDE2A
SCHEMBL25155354 0.84 IDO1 (0.39) SMN1; SMN2IDO1PDE2A
SCHEMBL25155772 0.76 NQO2 (0.41) MAPTBCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250025443-A1 COMPOUNDS AND METHODS FOR TREATING CORONA VIRUSES Clear Creek Bio, Inc. (US) 2025-01-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250025443-A1 COMPOUNDS AND METHODS FOR TREATING CORONA VIRUSES ACE, PREP, PEPD SMN1; SMN2 4601/4885IDO1 382/4885RAB9A 3136/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.