Zoxazolamine

Zoxazolamine

SCHEMBL251567

Nc1nc2cc(Cl)ccc2o1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 2/20 1.00
▸ CYP1A2 P05177 2/20 1.00
▸ MAPT P10636 2/20 1.00
▸ THRB P10828 1/20 1.00
▸ ALOX15 P16050 1/20 1.00
▸ MAPK1 P28482 1/20 1.00
▸ PIK3CG P48736 2/20 0.72
▸ PSMB8 P28062 2/20 0.61
▸ SMN1; SMN2 Q16637 3/20 0.54
▸ CASP3 P42574 2/20 0.54
▸ SENP7 Q9BQF6 2/20 0.54
▸ SENP6 Q9GZR1 2/20 0.54
▸ KDM4E B2RXH2 5/20 0.51
▸ ALDH1A1 P00352 3/20 0.51
▸ HPGD P15428 2/20 0.51
▸ NFKB1 P19838 1/20 0.51
▸ NFKB2 Q00653 1/20 0.51
▸ RELA Q04206 1/20 0.51
▸ MEN1 O00255 1/20 0.50
▸ KMT2A Q03164 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Zoxazolamine SCHEMBL10891033 1.00 LMNA (1.00) LMNACYP1A2MAPTTHRBALOX15
Zoxazolamine SCHEMBL29378757 1.00 LMNA (1.00) LMNACYP1A2MAPTTHRBALOX15
Zoxazolamine SCHEMBL10840280 0.90 LMNA (0.81) LMNACYP1A2MAPTTHRBALOX15
SCHEMBL17267694 0.85 MAPT (0.74) LMNACYP1A2MAPTTHRBALOX15
SCHEMBL30386387 0.85 MAPT (0.74) LMNACYP1A2MAPTTHRBALOX15
SCHEMBL9896463 0.84 PIK3CG (1.00) LMNACYP1A2MAPTTHRBALOX15
SCHEMBL30387074 0.81 CYP1A2 (0.68) LMNACYP1A2MAPTTHRBALOX15
SCHEMBL28563412 0.81 CYP1A2 (0.68) LMNACYP1A2MAPTTHRBALOX15
Simazine SCHEMBL3356949 0.80 LMNA (0.64) LMNACYP1A2MAPTTHRBALOX15
SCHEMBL16011443 0.80 LMNA (0.65) LMNACYP1A2MAPTTHRBALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 904 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117810644-B Polyimide lithium ion battery diaphragm and preparation method thereof 深圳市博盛新材料有限公司 2024-04-26 — — CN claimed
CN-117810644-A Polyimide lithium ion battery diaphragm and preparation method thereof 深圳市博盛新材料有限公司 2024-04-02 — — CN claimed
CN-116650618-A Use of secreted polypeptide in preparation of medicine for relieving diabetes and neuropathy thereof 复旦大学附属华山医院 2023-08-29 — — CN claimed
CN-116617358-A Application of secreted polypeptide in preparation of medicine for relieving diabetic complications 复旦大学附属华山医院 2023-08-22 — — CN claimed
CN-110506053-B Identification of cyclic peptide agonists of galanin receptors 2 and 3 directed by the structure of a flexin solution 香港浸会大学 2023-08-01 — — CN claimed
CN-110272925-B Enzymatic preparation method of suvorexant key intermediate 中国科学院天津工业生物技术研究所 2021-11-23 — — CN claimed
EP-2459227-B1 Prodrugs containing an aromatic amine connected by an amide bond to a carrier ASCENDIS PHARMA AS (DK) 2021-03-17 — — EP claimed
US-9173953-B2 Prodrugs containing an aromatic amine connected by an amido bond to a linker ASCENDIS PHARMA AS (DK) 2015-11-03 — — US claimed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 — — US claimed
EP-1904439-B1 SPHINGOSINE KINASE INHIBITORS APOGEE BIOTHECHNOLOGY CORP (US) 2014-11-26 — — EP claimed
WO-1999028316-A1 THIOPHENE-SULFONAMIDE COMPOUNDS PHARMACIA & UPJOHN S.P.A. (IT) 1999-06-10 — — WO claimed
WO-1998058562-A1 TOOTHBRUSH HAVING HEAD WITH PEEL-RESISTANT JOINT COLGATE-PALMOLIVE COMPANY (US) 1998-12-30 — — WO claimed
US-4923898-A Analgesic, anti-inflammatory and skeletal muscle relaxant compositions comprising non-steroidal anti-inflammatory drugs and musculoskeletal relaxants and methods of using same ANALGESIC ASSOCIATES (US) 1990-05-08 — — US claimed
EP-0205492-A1 ANALGESIC, ANTI-INFLAMMATORY AND SKELETAL MUSCLE RELAXANT COMPOSITIONS SUNSHINE, Abraham (US) 1986-12-30 — — EP claimed
WO-1986003681-A1 ANALGESIC, ANTI-INFLAMMATORY AND SKELETAL MUSCLE RELAXANT COMPOSITIONS SUNSHINE ABRAHAM 1986-07-03 — — WO claimed
EP-0087457-A4 GRAPHITIZATION SYSTEM METHOD AND APPARATUS. GREAT LAKES CARBON CORP (US) 1984-06-29 — — EP claimed
EP-0087457-A1 GRAPHITIZATION SYSTEM METHOD AND APPARATUS. GREAT LAKES CARBON CORP (US) 1983-09-07 — — EP claimed
WO-1983000549-A1 GRAPHITIZATION SYSTEM METHOD AND APPARATUS GREAT LAKES CARBON CORP (US) 1983-02-17 — — WO claimed
US-4189463-A Immunoassay for zoxazolamine HOFFMANN-LA ROCHE INC. (US) 1980-02-19 — — US claimed
US-3933498-A Fogged, direct positive silver halide emulsions containing a bleach inhibiting compound and a Dmin maintainer compound E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-01-20 — — US claimed
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