Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | MAPT | P10636 | 1/20 | 0.68 |
| ▸ | THRB | P10828 | 1/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.54 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.52 |
| ▸ | BACE1 | P56817 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.45 |
| ▸ | RELA | Q04206 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30387074 | 1.00 | CYP1A2 (0.68) | CYP1A2LMNAMAPTTHRBALOX15 | |
| SCHEMBL30386387 | 0.85 | MAPT (0.74) | CYP1A2LMNAMAPTTHRBALOX15 | |
| SCHEMBL17267694 | 0.85 | MAPT (0.74) | CYP1A2LMNAMAPTTHRBALOX15 | |
| SCHEMBL12850681 | 0.85 | LMNA (0.66) | CYP1A2LMNAMAPTTHRBALOX15 | |
| SCHEMBL14097677 | 0.83 | GAA (0.65) | CYP1A2LMNAMAPTTHRBALOX15 | |
| SCHEMBL31119195 | 0.83 | GAA (0.65) | CYP1A2LMNAMAPTTHRBALOX15 | |
| Zoxazolamine SCHEMBL251567 | 0.81 | LMNA (1.00) | CYP1A2LMNAMAPTTHRBALOX15 | |
| Zoxazolamine SCHEMBL29378757 | 0.81 | LMNA (1.00) | CYP1A2LMNAMAPTTHRBALOX15 | |
| Zoxazolamine SCHEMBL10891033 | 0.81 | LMNA (1.00) | CYP1A2LMNAMAPTTHRBALOX15 | |
| SCHEMBL23606777 | 0.80 | SMN1; SMN2 (0.77) | CYP1A2LMNAMAPTSMN1; SMN2CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112209894-B | 5-aryl substituted 2-aminobenzoxazole derivative, preparation method and application thereof | 贵州医科大学 | 2023-06-06 | — | — | CN | disclosed |
| CN-112209894-A | 5-aryl substituted 2-aminobenzoxazole derivative, preparation method and application thereof | 贵州医科大学 | 2021-01-12 | — | — | CN | disclosed |