Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 10/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | CCNK | O75909 | 1/20 | 0.39 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15149825 | 0.87 | MEN1 (0.45) | CA2MAPK14APPMAPTTP53 | |
| SCHEMBL9644921 | 0.87 | MEN1 (0.45) | CA2MAPK14APPMAPTTP53 | |
| SCHEMBL4656183 | 0.85 | CA2 (0.44) | CA2MAPK14APPMAPTTP53 | |
| SCHEMBL30372486 | 0.84 | TP53 (0.49) | CA2MAPK14APPMAPTTP53 | |
| SCHEMBL898113 | 0.84 | CA2 (0.45) | CA2MAPK14APPMAPTTP53 | |
| SCHEMBL13204672 | 0.84 | PKM (0.51) | CA2MAPK14APPMAPTTP53 | |
| SCHEMBL6267008 | 0.84 | PKM (0.51) | CA2MAPK14APPMAPTTP53 | |
| SCHEMBL898114 | 0.84 | CA2 (0.45) | CA2MAPK14APPMAPTTP53 | |
| SCHEMBL1076666 | 0.82 | CA2 (0.48) | CA2MAPK14APPMAPTTP53 | |
| SCHEMBL465772 | 0.82 | CA2 (0.48) | CA2MAPK14APPMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023061723-A1 | HYDROXYPHENYL-ETHYNYL-PHENOL DERIVATIVES AS AR (ANDROGEN RECEPTOR) TRANSCRIPTIONAL ACTIVITY MODULATORS FOR USE IN THE TREATMENT OF I.A. PROSTATE CANCER | FUNDACIÓ INSTITUT DE RECERCA BIOMÈDICA (IRB BARCELONA) (ES) | 2023-04-20 | — | — | WO | disclosed |