Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.30 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.30 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.30 |
| ▸ | DAO | P14920 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20644439 | 0.87 | PRMT5 (0.37) | — | |
| SCHEMBL21538539 | 0.82 | TDP1 (0.32) | TDP1 | |
| SCHEMBL25160177 | 0.81 | TLR7 (0.32) | TDP1TLR7P2RX3P2RX2DAO | |
| SCHEMBL25160125 | 0.79 | MAPT (0.37) | TDP1 | |
| SCHEMBL20644372 | 0.75 | NPBWR1 (0.35) | — | |
| SCHEMBL25160033 | 0.73 | MAPT (0.51) | — | |
| SCHEMBL20652846 | 0.73 | MAPT (0.51) | — | |
| SCHEMBL23709213 | 0.73 | MAPT (0.51) | — | |
| SCHEMBL12191943 | 0.73 | MAPT (0.51) | — | |
| SCHEMBL20644460 | 0.73 | CNR1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3397629-B1 | METALLOENZYME INHIBITOR COMPOUNDS | NQP 1598 LTD (KY) | 2023-04-19 | — | — | EP | disclosed |