Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.32 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20644385 | 0.87 | PRMT5 (0.38) | PRMT5WDR77 | |
| SCHEMBL21538417 | 0.82 | MAPT (0.50) | PRMT5WDR77TP53MAPT | |
| SCHEMBL25160115 | 0.81 | TDP1 (0.31) | TLR7P2RX3P2RX2DAOTDP1 | |
| SCHEMBL25160271 | 0.76 | MAPT (0.48) | TP53MAPTTDP1 | |
| SCHEMBL20644471 | 0.73 | SMN1; SMN2 (0.36) | PRMT5WDR77TP53MAPT | |
| SCHEMBL25160112 | 0.71 | RGS4 (0.34) | MAPT | |
| SCHEMBL25160125 | 0.68 | MAPT (0.37) | TP53MAPTTDP1 | |
| SCHEMBL20644439 | 0.68 | PRMT5 (0.37) | PRMT5WDR77 | |
| SCHEMBL20644462 | 0.68 | — | — | |
| SCHEMBL21985427 | 0.66 | POLB (0.44) | TLR7TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3397629-B1 | METALLOENZYME INHIBITOR COMPOUNDS | NQP 1598 LTD (KY) | 2023-04-19 | — | — | EP | disclosed |