Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20644408 | 0.90 | MAPT (0.31) | MAPTKDM4EALDH1A1LMNAGAA | |
| SCHEMBL25160125 | 0.80 | MAPT (0.37) | TDP1MAPTKDM4EALDH1A1LMNA | |
| SCHEMBL20644382 | 0.80 | MAPT (0.33) | MAPTKDM4EALDH1A1LMNAGAA | |
| SCHEMBL20644580 | 0.78 | LMNA (0.33) | MAPTLMNAGAA | |
| SCHEMBL20644386 | 0.78 | — | — | |
| SCHEMBL20644605 | 0.75 | KDM4E (0.31) | MAPTKDM4EALDH1A1LMNAGAA | |
| SCHEMBL20644380 | 0.74 | PRMT5 (0.30) | — | |
| SCHEMBL20644511 | 0.71 | MAPT (0.33) | MAPTKDM4EALDH1A1LMNAGAA | |
| SCHEMBL25160279 | 0.71 | MAPT (0.37) | MAPTKDM4EALDH1A1LMNAGAA | |
| SCHEMBL20644563 | 0.71 | MAPT (0.37) | MAPTKDM4EALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3397629-B1 | METALLOENZYME INHIBITOR COMPOUNDS | NQP 1598 LTD (KY) | 2023-04-19 | — | — | EP | disclosed |