Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MPL | P40238 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.33 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP3 | Q9H4L4 | 1/20 | 0.33 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22444090 | 0.87 | MYC (0.40) | MYCTSHRSMN1; SMN2CASP1LMNA | |
| Iodide SCHEMBL28419660 | 0.86 | MYC (0.39) | MYCTSHRSMN1; SMN2RCE1CASP1 | |
| SCHEMBL28736762 | 0.86 | MYC (0.39) | MYCTSHRSMN1; SMN2RCE1CASP1 | |
| SCHEMBL8523878 | 0.84 | ELANE (0.45) | MYCTSHRSMN1; SMN2RCE1LMNA | |
| SCHEMBL5597379 | 0.83 | MYC (0.37) | MYCTSHRSMN1; SMN2RCE1CASP1 | |
| SCHEMBL28348395 | 0.82 | PRKAB2 (0.40) | SMN1; SMN2LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL4838484 | 0.78 | ALDH1A1 (0.49) | TSHRSMN1; SMN2MAPTALDH1A1KMT2A | |
| SCHEMBL28166154 | 0.77 | TSHR (0.36) | MYCTSHRSMN1; SMN2RCE1CASP1 | |
| SCHEMBL20875060 | 0.77 | ATM (0.41) | MYCCASP1LMNAKMT2AMAOB | |
| SCHEMBL27534698 | 0.77 | BACE1 (0.44) | TSHRSMN1; SMN2LMNAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2365974-B1 | FLUORINATED BENZOTHIAZOLE DERIVATIVES, PREPARATION METHOD THEREOF AND IMAGING AGENT FOR DIAGNOSING ALTZHEIMER'S DISEASE USING THE SAME | SNU R&DB FOUNDATION (KR) | 2013-12-25 | — | — | EP | claimed |
| EP-2365974-B1 | FLUORINATED BENZOTHIAZOLE DERIVATIVES, PREPARATION METHOD THEREOF AND IMAGING AGENT FOR DIAGNOSING ALTZHEIMER'S DISEASE USING THE SAME | SNU R&DB FOUNDATION (KR) | 2013-12-25 | — | — | EP | disclosed |
| US-20110250136-A1 | FLUORINATED BENZOTHIAZOLE DERIVATIVES, PREPARATION METHOD THEREOF AND IMAGING AGENT FOR DIAGNOSING ALTZHEIMER'S DISEASE USING THE SAME | SNU R&DB FOUNDATION (KR) | 2011-10-13 | — | — | US | disclosed |
| EP-2365974-A1 | FLUORINATED BENZOTHIAZOLE DERIVATIVES, PREPARATION METHOD THEREOF AND IMAGING AGENT FOR DIAGNOSING ALTZHEIMER'S DISEASE USING THE SAME | SNU R&DB Foundation (KR) | 2011-09-21 | — | — | EP | disclosed |
| WO-2010053218-A1 | FLUORINATED BENZOTHIAZOLE DERIVATIVES, PREPARATION METHOD THEREOF AND IMAGING AGENT FOR DIAGNOSING ALTZHEIMER'S DISEASE USING THE SAME | SNU R&DB FOUNDATION (KR) | 2010-05-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110250136-A1 | FLUORINATED BENZOTHIAZOLE DERIVATIVES, PREPARATION METHOD THEREOF AND IMAGING AGENT FOR DIAGNOSING ALTZHEIMER'S DISEASE USING THE SAME | APBA1, APP, PSEN1 | MYC 4697/4885TSHR 4126/4885SMN1; SMN2 1366/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.