Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.41 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9806686 | 0.84 | FFAR1 (0.43) | ATML3MBTL1THRBALDH1A1FKBP1A | |
| SCHEMBL1779547 | 0.83 | L3MBTL1 (0.38) | ATML3MBTL1ALDH1A1FKBP1ARAB9A | |
| SCHEMBL12606506 | 0.83 | CHRM2 (0.41) | ATML3MBTL1FKBP1APOLB | |
| SCHEMBL3035722 | 0.83 | L3MBTL1 (0.38) | ATML3MBTL1ALDH1A1FKBP1ARAB9A | |
| SCHEMBL1046911 | 0.82 | KDM1A (0.44) | ATMALDH1A1FKBP1A | |
| SCHEMBL1050048 | 0.82 | KDM1A (0.44) | ATMALDH1A1FKBP1A | |
| SCHEMBL79593 | 0.82 | KDM1A (0.44) | ATMALDH1A1FKBP1A | |
| SCHEMBL21057416 | 0.82 | KDM4E (0.52) | ATML3MBTL1THRBALDH1A1FKBP1A | |
| SCHEMBL18431147 | 0.82 | RAB9A (0.48) | ATML3MBTL1THRBALDH1A1GABRA1 | |
| SCHEMBL16606343 | 0.82 | L3MBTL1 (0.35) | ATML3MBTL1ALDH1A1FKBP1AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230117289-A1 | COMPOSITIONS COMPRISING METHYLPHENIDATE-PRODRUGS, PROCESSES OF MAKING AND USING THE SAME | COMMAVE THERAPEUTICS SA (CH) | 2023-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230117289-A1 | COMPOSITIONS COMPRISING METHYLPHENIDATE-PRODRUGS, PROCESSES OF MAKING AND USING THE SAME | COMT, CYP3A4, CYP2C19 | ATM 981/4885L3MBTL1 3653/4885THRB 579/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.