Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 3/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21276535 | 0.76 | MAPK1 (0.39) | PREPCHRM2CHRM1CHRM3NPC1 | |
| SCHEMBL25166086 | 0.75 | USP30 (0.38) | PREPNPC1UCHL1GPR119GRM5 | |
| SCHEMBL31457954 | 0.74 | GPR119 (0.35) | CHRM2CHRM1CHRM3NPC1GPR119 | |
| SCHEMBL12069963 | 0.73 | PDK4 (0.50) | GRM5PDK4 | |
| SCHEMBL19390105 | 0.73 | CHRM2 (0.38) | CHRM2CHRM1CHRM3ELANEHSD17B10 | |
| SCHEMBL23415868 | 0.73 | CHRM2 (0.38) | CHRM2CHRM1CHRM3ELANEHSD17B10 | |
| SCHEMBL17409654 | 0.73 | PREP (0.43) | PREPCHRM2CHRM1CHRM3NPC1 | |
| SCHEMBL24700152 | 0.72 | GRM5 (0.42) | UCHL1GPR119GRM5PDK4 | |
| SCHEMBL18198355 | 0.72 | SETD7 (0.39) | PREPCHRM2CHRM1CHRM3NPC1 | |
| SCHEMBL4175218 | 0.71 | CHRM2 (0.44) | PREPCHRM2CHRM1CHRM3GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023064586-A1 | NOVEL MODULATORS OF EHMT1 AND EHMT2 AND THERAPEUTIC USE THEREOF | TANGO THERAPEUTICS, INC. (US) | 2023-04-20 | — | — | WO | disclosed |