Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26765821 | 0.83 | PREP (0.41) | PREPCHRM2CHRM1CHRM3HSD17B10 | |
| SCHEMBL30477339 | 0.83 | PREP (0.41) | PREPCHRM2CHRM1CHRM3HSD17B10 | |
| SCHEMBL25124058 | 0.80 | CHRM2 (0.36) | PREPCHRM2CHRM1CHRM3ATM | |
| SCHEMBL31460207 | 0.79 | PREP (0.39) | PREPCHRM2CHRM1CHRM3ATM | |
| SCHEMBL4175218 | 0.75 | CHRM2 (0.44) | PREPCHRM2CHRM1CHRM3HSD17B10 | |
| SCHEMBL489128 | 0.75 | CHRM2 (0.44) | PREPCHRM2CHRM1CHRM3HSD17B10 | |
| SCHEMBL489126 | 0.75 | CHRM2 (0.44) | PREPCHRM2CHRM1CHRM3HSD17B10 | |
| SCHEMBL17664705 | 0.75 | PREP (0.38) | PREPCHRM2CHRM1CHRM3HSD17B10 | |
| SCHEMBL29866656 | 0.75 | PREP (0.39) | PREPCHRM2CHRM1CHRM3HSD17B10 | |
| SCHEMBL25165581 | 0.75 | PREP (0.39) | PREPCHRM2CHRM1CHRM3HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118647610-A | Novel modulators of EHMT1 and EHMT2 and therapeutic uses thereof | 探戈医药股份有限公司 | 2024-09-13 | — | — | CN | disclosed |
| EP-3459944-B1 | AZEPANYL-DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME WITH ANTIPARASITIC ACTIVITY | MERCK PATENT GMBH (DE) | 2021-01-06 | — | — | EP | disclosed |
| EP-3459944-A1 | AZEPANYL-DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME WITH ANTIPARASITIC ACTIVITY | Merck Patent GmbH (DE) | 2019-03-27 | — | — | EP | disclosed |
| US-9994577-B2 | Azepanyl-derivatives and pharmaceutical compositions comprising the same with antiparasitic activity | MERCK PATENT GMBH (DE) | 2018-06-12 | — | — | US | disclosed |
| US-9994577-B2 | Azepanyl-derivatives and pharmaceutical compositions comprising the same with antiparasitic activity | MERCK PATENT GMBH (DE) | 2018-06-12 | — | — | US | disclosed |
| US-20170137428-A1 | AZEPANYL-DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME WITH ANTIPARASITIC ACTIVITY | MERCK PATENT GMBH (DE) | 2017-05-18 | — | — | US | disclosed |
| US-20170137428-A1 | AZEPANYL-DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME WITH ANTIPARASITIC ACTIVITY | MERCK PATENT GMBH (DE) | 2017-05-18 | — | — | US | disclosed |
| WO-2016000827-A1 | AZEPANYL-DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME WITH ANTIPARASITIC ACTIVITY | MERCK PATENT GMBH (DE) | 2016-01-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170137428-A1 | AZEPANYL-DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME WITH ANTIPARASITIC ACTIVITY | ACHE, PARK7, CYP51A1 | PREP 740/4885CHRM2 390/4885CHRM1 493/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.