⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10885201 | 0.97 | HRH3 (0.62) | — | |
| SCHEMBL1788911 | 0.97 | HRH3 (0.62) | — | |
| SCHEMBL768306 | 0.97 | HRH3 (0.62) | — | |
| Water SCHEMBL7828726 | 0.97 | GNAI3 (0.56) | — | |
| SCHEMBL20033703 | 0.97 | HRH3 (0.62) | — | |
| SCHEMBL28384304 | 0.97 | HRH3 (0.62) | — | |
| SCHEMBL29385011 | 0.97 | HRH3 (0.62) | — | |
| SCHEMBL7478832 | 0.97 | HRH3 (0.62) | — | |
| SCHEMBL22121638 | 0.97 | HRH3 (0.62) | — | |
| Hydrochloric Acid SCHEMBL4249145 | 0.95 | GNAO1 (0.65) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4355729-A1 | AZETIDINYL COMPOUNDS COMPRISING A CARBOXYLIC ACID GROUP FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | Celgene Corporation (US) | 2024-04-24 | — | — | EP | disclosed |
| US-11919879-B2 | Carboxylic acid containing azetidinyl compounds for the treatment of neurodegenerative diseases | CELGENE CORPORATION (US) | 2024-03-05 | — | — | US | disclosed |
| CN-117500785-A | Azetidinyl-containing carboxylic acid compounds for the treatment of neurodegenerative diseases | 细胞基因公司 | 2024-02-02 | — | — | CN | disclosed |
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | disclosed |
| US-20230028747-A1 | Carboxylic Acid Containing Azetidinyl Compounds for the Treatment of Neurodegenerative Diseases | CELGENE CORPORATION (US) | 2023-01-26 | — | — | US | disclosed |
| WO-2022266162-A1 | AZETIDINYL COMPOUNDS COMPRISING A CARBOXYLIC ACID GROUP FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | CELGENE CORPORATION (US) | 2022-12-22 | — | — | WO | disclosed |
| CN-108484468-A | The preparation method of aryl azetidin compounds | 南京大学 | 2018-09-04 | — | — | CN | disclosed |
| CN-108484468-A | The preparation method of aryl azetidin compounds | 南京大学 | 2018-09-04 | — | — | CN | disclosed |
| EP-2601190-B1 | ISOXAZOLINE DERIVATIVES AS ANTIPARASITIC AGENTS | ZOETIS SERVICES LLC (US) | 2018-07-04 | — | — | EP | disclosed |
| US-20170334841-A1 | TETRACYCLINE COMPOUNDS | TETRAPHASE PHARMACEUTICALS, INC. | 2017-11-23 | — | — | US | disclosed |
| WO-2000075203-A1 | PROCESS FOR PRODUCING ETHYLENE/OLEFIN INTERPOLYMERS | EASTMAN CHEMICAL COMPANY (US) | 2000-12-14 | — | — | WO | disclosed |
| WO-2000075202-A1 | PROCESS FOR PRODUCING ETHYLENE/OLEFIN INTERPOLYMERS | EASTMAN CHEMICAL COMPANY (US) | 2000-12-14 | — | — | WO | disclosed |
| WO-2000052068-A1 | PROCESS FOR PRODUCING POLYETHYLENE | EASTMAN CHEMICAL COMPANY (US) | 2000-09-08 | — | — | WO | disclosed |
| EP-0900236-A1 | PHOTOPOLYMERIZATION REACTIONS INDUCED BY CHEMILUMINESCENCE | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1999-03-10 | — | — | EP | disclosed |
| WO-1997033922-A1 | PHOTOPOLYMERIZATION REACTIONS INDUCED BY CHEMILUMINESCENCE | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-09-18 | — | — | WO | disclosed |
| US-5494944-A | BLEND OF MATERIAL POLYMERIZABLE BY FREE RADICAL CATALYSTAND AN IRON COMPOUND | CIBA-GEIGY CORPORATION (US) | 1996-02-27 | — | — | US | disclosed |
| US-5371115-A | Having sensitizers, electron acceptors selected from peracids, hydroperoxides and quinones; photosensitive, photoresists | CIBA-GEIGY CORPORATION (US) | 1994-12-06 | — | — | US | disclosed |
| US-5073476-A | Containing iron aromatic complex and oxidizer | CIBA-GEIGY CORPORATION (US) | 1991-12-17 | — | — | US | disclosed |
| EP-0375527-A1 | N-aryl-azetidinones, process for their preparation and their use as elastase inhibitors | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 1990-06-27 | — | — | EP | disclosed |
| US-4868288-A | TITANIUM TETRACHLORIDE CATALYST | CIBA-GEIGY CORPORATION (US) | 1989-09-19 | — | — | US | disclosed |