Benorilate

Benorilate

SCHEMBL25167

CC(=O)Nc1ccc(OC(=O)c2ccccc2OC(C)=O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 5/20 0.70
HPGD P15428 4/20 0.70
ALDH1A1 P00352 4/20 0.68
KDM4E B2RXH2 3/20 0.68
GLA P06280 1/20 0.68
PTGS2 P35354 2/20 0.61
LMNA P02545 1/20 0.57
CYP1A2 P05177 1/20 0.57
CYP2C9 P11712 1/20 0.57
MAPT P10636 2/20 0.57
KMT2A Q03164 8/20 0.57
MEN1 O00255 3/20 0.57
TSHR P16473 2/20 0.53
SMN1; SMN2 Q16637 1/20 0.52
ESR1 P03372 1/20 0.51
ITGB3 P05106 1/20 0.51
ITGA2B P08514 1/20 0.51
HMGB1 P09429 1/20 0.51
GGT1 P19440 1/20 0.51
PTGS1 P23219 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benorilate SCHEMBL27446831 1.00 HSD17B10 (0.70) HSD17B10HPGDALDH1A1KDM4EGLA
Benorilate SCHEMBL15526470 1.00 HSD17B10 (0.70) HSD17B10HPGDALDH1A1KDM4EGLA
Benorilate SCHEMBL15969775 0.99 HSD17B10 (0.68) HSD17B10HPGDALDH1A1KDM4EGLA
Benorilate SCHEMBL1162333 0.95 HSD17B10 (0.68) HSD17B10HPGDALDH1A1KDM4EGLA
Benorilate SCHEMBL28324024 0.91 HSD17B10 (0.60) HSD17B10HPGDALDH1A1KDM4EGLA
Benorilate SCHEMBL28086366 0.89 MAPK1 (0.61) HSD17B10HPGDALDH1A1KDM4EGLA
SCHEMBL13243355 0.89 HPGD (0.70) HSD17B10HPGDALDH1A1KDM4EGLA
Benorilate SCHEMBL28008209 0.88 PTGS2 (0.59) HSD17B10HPGDALDH1A1KDM4EGLA
SCHEMBL29277083 0.85 PTGS2 (0.55) HSD17B10HPGDALDH1A1KDM4EGLA
SCHEMBL11320907 0.84 HPGD (0.57) HSD17B10HPGDALDH1A1KDM4EGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 11695 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4724049-A1 MODIFIED RELEASE FILL COMPOSITIONS FOR DOSAGE FORMS AND METHODS OF PREPARATION AND USE THEREOF Catalent Ontario Limited (CA) 2026-04-15 EP claimed
US-20260069532-A1 METHOD FOR MORSELIZING AND/OR TARGETING PHARMACEUTICALLY ACTIVE PRINCIPLES TO SYNOVIAL TISSUE MEDINCELL S.A. (FR) 2026-03-12 US claimed
US-12558309-B2 Method for morselizing and/or targeting pharmaceutically active principles to synovial tissue MEDINCELL S.A. (FR) 2026-02-24 US claimed
EP-4482481-B1 COMPOUNDS FOR USE IN THE TREATMENT OF DYSTROPHINOPATHIES SOM INNOVATION BIOTECH S A (ES) 2025-11-12 EP claimed
WO-2025224317-A1 A METHOD FOR TARGETING PHARMACEUTICALLY ACTIVE PRINCIPLE IN TOTAL KNEE REPLACEMENT MEDINCELL S.A. (FR) 2025-10-30 WO claimed
EP-4615506-A1 USE OF GSK-3 ACTIVATIOR TO MODULATE PROTEASOME ACTIVITY TO PREVENT AGEING ASSOCIATED CONDITIONS AND DISEASES Sahin, Fikret (TR) 2025-09-17 EP claimed
US-20250255781-A1 PROCESSES FOR PREPARATION OF 3-D PRINTED PHARMACEUTICAL PRODUCTS BRISTOL-MYERS SQUIBB COMPANY (US) 2025-08-14 US claimed
US-20250152567-A1 COMPOUNDS FOR USE IN THE TREATMENT OF DYSTROPHINOPATHIES REGENTS OF THE UNIVERSITY OF MINNESOTA 2025-05-15 US claimed
US-12296043-B2 Liquisoft capsules PATHEON SOFTGELS INC. (US) 2025-05-13 US claimed
CN-119770461-A Preparation method of amphiphilic high-amylose corn grafted starch nanofiber drug-loaded membrane 安徽工程大学 2025-04-08 CN claimed
EP-0268388-B1 ANTI-INFLAMMATORY COMPOSITIONS GLAXO GROUP LIMITED (GB) 1992-07-22 EP claimed
US-4855293-A Anti-inflammatory compositions comprising a systemic non-steroidal anti-inflammatory drug and a cyclopentyl ether GLAXO GROUP LIMITED (GB) 1989-08-08 US claimed
EP-0100168-B1 PROCESSES FOR PREPARING TABLETS BY A MODIFIED 'WET-GRANULATION' TECHNIQUE Rogerson, Alan George (GB) 1988-12-28 EP claimed
EP-0268388-A1 Anti-inflammatory compositions GLAXO GROUP LIMITED (GB) 1988-05-25 EP claimed
CN-85109571-A The method of one-step synthesis antirheumatic benoral 1987-07-08 CN claimed
EP-0093520-B1 PHARMACEUTICAL COMPOSITIONS AND PREPARATION THEREOF NORISTAN LIMITED (ZA) 1986-10-15 EP claimed
US-4562024-A HOMOGENIZING PART OF SOLID WITH GRANULATING FLUID TO FORM UNIFORM SLURRY, MOISTENING REST OF SOLID WITH SLURRY FORMED STERLING DRUG INC. (US) 1985-12-31 US claimed
EP-0100168-A2 Processes for preparing tablets by a modified 'wet-granulation' technique Rogerson, Alan George (GB) 1984-02-08 EP claimed
EP-0093520-A1 Pharmaceutical compositions and preparation thereof NORISTAN LIMITED (ZA) 1983-11-09 EP claimed
US-4378354-A CONSISTING OF A PHOSPHOLIPID AND SALICYLIC ACID OR DERIVATIVE A. NATTERMANN & CIE. GMBH (DE) 1983-03-29 US claimed