Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.57 |
| ▸ | HPGD | P15428 | 6/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.51 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.51 |
| ▸ | GGT1 | P19440 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benorilate SCHEMBL1162333 | 0.92 | HSD17B10 (0.68) | HSD17B10HPGDKDM4ELMNACYP1A2 | |
| Benorilate SCHEMBL25167 | 0.89 | HSD17B10 (0.70) | HSD17B10HPGDKDM4ELMNACYP1A2 | |
| Benorilate SCHEMBL27446831 | 0.89 | HSD17B10 (0.70) | HSD17B10HPGDKDM4ELMNACYP1A2 | |
| Benorilate SCHEMBL15526470 | 0.89 | HSD17B10 (0.70) | HSD17B10HPGDKDM4ELMNACYP1A2 | |
| Benorilate SCHEMBL15969775 | 0.88 | HSD17B10 (0.68) | HSD17B10HPGDKDM4ELMNACYP1A2 | |
| Benorilate SCHEMBL28324024 | 0.84 | HSD17B10 (0.60) | HSD17B10HPGDKDM4ELMNACYP1A2 | |
| Benorilate SCHEMBL5495943 | 0.79 | HSD17B10 (0.57) | HSD17B10HPGDKDM4ELMNACYP1A2 | |
| SCHEMBL13243355 | 0.79 | HPGD (0.70) | MAPK1HSD17B10HPGDKDM4ELMNA | |
| Benorilate SCHEMBL28008209 | 0.79 | PTGS2 (0.59) | HSD17B10HPGDKDM4ELMNACYP1A2 | |
| Dipyrocetyl SCHEMBL29508594 | 0.78 | MAPK1 (1.00) | MAPK1HSD17B10HPGDKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103717597-B | Heterocyclic compounds as kinase inhibitors | 原真股份有限公司 | 2017-07-04 | — | — | CN | disclosed |
| CN-103492389-B | Pyrazolo [4,3-d] pyrimidine as inhibitors of kinases | 原真股份有限公司 | 2016-09-14 | — | — | CN | disclosed |