Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | GFER | P55789 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25442725 | 0.85 | MAPT (0.55) | MAPTRAB9AHPGDGFERALDH1A1 | |
| SCHEMBL25166952 | 0.82 | MAPT (0.44) | MAPTRAB9AHPGDGFERALDH1A1 | |
| SCHEMBL25442724 | 0.75 | RAB9A (0.53) | MAPTRAB9AHPGDGFERALDH1A1 | |
| SCHEMBL25167895 | 0.74 | MAPT (0.48) | MAPTRAB9AHPGDGFERALDH1A1 | |
| SCHEMBL25168109 | 0.73 | RAB9A (0.57) | MAPTRAB9AHPGDGFERALDH1A1 | |
| SCHEMBL25442728 | 0.72 | HPGD (0.50) | MAPTRAB9AHPGDGFERALDH1A1 | |
| SCHEMBL25442727 | 0.71 | HPGD (0.49) | MAPTRAB9AHPGDGFERALDH1A1 | |
| SCHEMBL11593766 | 0.71 | MAPT (0.81) | MAPTRAB9AHPGDGFERALDH1A1 | |
| SCHEMBL27961398 | 0.70 | TRPV1 (0.59) | TRPV1DGAT1 | |
| SCHEMBL25442712 | 0.69 | RAB9A (0.60) | MAPTRAB9AHPGDGFERALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4177246-A1 | FUSED OXAZEPINES AS INHIBITORS OF PEROXIREDOXINS | Centro Atlántico del Medicamento, SA (ES) | 2023-05-10 | — | — | EP | disclosed |
| EP-4177246-A1 | FUSED OXAZEPINES AS INHIBITORS OF PEROXIREDOXINS | Centro Atlántico del Medicamento, SA (ES) | 2023-05-10 | — | — | EP | disclosed |