Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | GFER | P55789 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25442728 | 0.85 | HPGD (0.50) | RAB9ANPC1SMN1; SMN2PKMMAPT | |
| SCHEMBL25167895 | 0.79 | MAPT (0.48) | RAB9ANPC1SMN1; SMN2PKMMAPT | |
| SCHEMBL25442725 | 0.78 | MAPT (0.55) | RAB9ANPC1SMN1; SMN2PKMMAPT | |
| SCHEMBL25442727 | 0.76 | HPGD (0.49) | RAB9ANPC1SMN1; SMN2PKMMAPT | |
| SCHEMBL25167178 | 0.75 | MAPT (0.49) | RAB9ANPC1SMN1; SMN2PKMMAPT | |
| SCHEMBL29036800 | 0.73 | CYP2C19 (0.56) | CYP2C19TDO2 | |
| SCHEMBL25168109 | 0.73 | RAB9A (0.57) | RAB9ANPC1SMN1; SMN2PKMMAPT | |
| SCHEMBL5194552 | 0.72 | CA12 (0.69) | PKMKDM4ECA12CA2CA9 | |
| SCHEMBL11593766 | 0.71 | MAPT (0.81) | RAB9ANPC1SMN1; SMN2MAPTHPGD | |
| SCHEMBL25166952 | 0.71 | MAPT (0.44) | RAB9ANPC1SMN1; SMN2PKMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4177246-A1 | FUSED OXAZEPINES AS INHIBITORS OF PEROXIREDOXINS | Centro Atlántico del Medicamento, SA (ES) | 2023-05-10 | — | — | EP | disclosed |