Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 10/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | FGFR3 | P22607 | 5/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 4/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23725835 | 0.89 | KDR (0.36) | KDRKDM4EALDH1A1GAAPKM | |
| SCHEMBL23725543 | 0.87 | ALDH1A1 (0.35) | KDRKDM4EALDH1A1GAAPKM | |
| SCHEMBL23726936 | 0.82 | KDR (0.40) | KDRKDM4EALDH1A1GAAPKM | |
| SCHEMBL23727338 | 0.81 | JAK2 (0.32) | KDRKDM4EALDH1A1GAAPKM | |
| SCHEMBL23725760 | 0.78 | FLT3 (0.34) | KDRKDM4EALDH1A1FLT3FGFR3 | |
| SCHEMBL25168867 | 0.76 | SSTR4 (0.42) | KDRKDM4EALDH1A1GAAPKM | |
| SCHEMBL30432339 | 0.76 | SSTR4 (0.42) | KDRKDM4EALDH1A1GAAPKM | |
| SCHEMBL23727423 | 0.74 | HAT1 (0.30) | FLT3 | |
| SCHEMBL25168030 | 0.72 | SSTR4 (0.42) | KDRKDM4EALDH1A1GAAPKM | |
| SCHEMBL30433252 | 0.72 | SSTR4 (0.42) | KDRKDM4EALDH1A1GAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230143612-A1 | SUBSTITUTED 1,1'-BIPHENYL COMPOUNDS AND METHODS USING SAME | ARBUTUS BIOPHARMA CORP (US) | 2023-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230143612-A1 | SUBSTITUTED 1,1'-BIPHENYL COMPOUNDS AND METHODS USING SAME | HAVCR2, HMBS, VHL | KDR 3652/4885KDM4E 224/4885ALDH1A1 172/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.