SCHEMBL25168080

SCHEMBL25168080

O=P(O)(O)OP(=O)(OC[C@H]1O[C@@H](n2cnc3c(O)ncnc32)[C@H](O)[C@@H]1O)OC[C@H]1O[C@@H](n2cnc3c(O)ncnc32)[C@H](O)[C@@H]1O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P2RY1 P47900 5/20 0.67
DNPH1 O43598 5/20 0.67
P2RY2 P41231 3/20 0.67
SRC P12931 2/20 0.67
SMN1; SMN2 Q16637 2/20 0.67
TRPM2 O94759 2/20 0.67
TAS1R3 Q7RTX0 2/20 0.67
TAS1R1 Q7RTX1 2/20 0.67
PRKAB2 O43741 1/20 0.67
LDHA P00338 1/20 0.67
ADRB2 P07550 1/20 0.67
FBP1 P09467 1/20 0.67
ADORA1 P30542 1/20 0.67
PRKAG1 P54619 1/20 0.67
PRKAA2 P54646 1/20 0.67
PDE4D Q08499 1/20 0.67
KCNH2 Q12809 1/20 0.67
PRKAA1 Q13131 1/20 0.67
PDE3A Q14432 1/20 0.67
P2RY11 Q96G91 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27742698 0.98 P2RY1 (0.67) P2RY1DNPH1P2RY2SRCSMN1; SMN2
SCHEMBL27579244 0.96 P2RY1 (0.65) P2RY1DNPH1P2RY2SRCSMN1; SMN2
SCHEMBL27789055 0.94 P2RY1 (0.78) P2RY1DNPH1P2RY2SRCSMN1; SMN2
SCHEMBL30112894 0.92 P2RX3 (0.74) P2RY1DNPH1P2RY2SRCSMN1; SMN2
Triphosphate SCHEMBL11814723 0.92 DNPH1 (0.73) P2RY1DNPH1P2RY2SRCSMN1; SMN2
SCHEMBL23711717 0.92 P2RX3 (0.74) P2RY1DNPH1P2RY2SRCSMN1; SMN2
SCHEMBL162915 0.92 P2RX3 (0.74) P2RY1DNPH1P2RY2SRCSMN1; SMN2
SCHEMBL162914 0.92 P2RX3 (0.74) P2RY1DNPH1P2RY2SRCSMN1; SMN2
SCHEMBL24145247 0.92 DNPH1 (0.79) P2RY1DNPH1P2RY2SRCSMN1; SMN2
SCHEMBL19255 0.92 DNPH1 (0.79) P2RY1DNPH1P2RY2SRCSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023080663-A1 METABOLITE MARKER FOR DIAGNOSIS OF MYCOBACTERIUM AVIUM COMPLEX INFECTIOUS DISEASE OR FOR PREDICTION OF SEVERITY 연세대학교 산학협력단 2023-05-11 WO disclosed