Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | PNMT | P11086 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
| ▸ | MMP16 | P51512 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | FABP3 | P05413 | 1/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6680955 | 0.83 | GAA (0.46) | CYP1A2CYP3A4CYP2D6NFKB1PNMT | |
| SCHEMBL9098597 | 0.83 | MYC (0.44) | MYCCYP1A2TTRMMP1MMP2 | |
| SCHEMBL27852913 | 0.83 | HSD11B1 (0.47) | MYCCYP1A2TTRCYP3A4MMP1 | |
| SCHEMBL29353004 | 0.83 | HSD11B1 (0.47) | MYCCYP1A2TTRCYP3A4MMP1 | |
| SCHEMBL9617134 | 0.83 | TTR (0.42) | MYCCYP1A2TTRNFKB1MMP1 | |
| SCHEMBL27273870 | 0.83 | TTR (0.42) | MYCCYP1A2TTRNFKB1MMP1 | |
| SCHEMBL29617 | 0.83 | HSD11B1 (0.47) | MYCCYP1A2TTRCYP3A4MMP1 | |
| Ammonia Solution, Strong SCHEMBL340600 | 0.82 | HSD11B1 (0.46) | MYCCYP1A2TTRCYP3A4MMP1 | |
| SCHEMBL22345145 | 0.82 | HSD11B1 (0.46) | MYCCYP1A2TTRCYP3A4MMP1 | |
| SCHEMBL5692778 | 0.82 | HSD11B1 (0.50) | MYCCYP1A2CYP3A4MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8034787-B2 | Enzyme-cleavable prodrug compounds | MEDAREX, INC. (US) | 2011-10-11 | — | — | US | disclosed |
| US-7816317-B2 | Tripeptide prodrug compounds | MEDAREX, INC. (US) | 2010-10-19 | — | — | US | disclosed |
| US-20090110753-A1 | Enzyme-cleavable prodrug compounds | MEDAREX, INC. (US) | 2009-04-30 | — | — | US | disclosed |
| US-20040198716-A1 | Cysteine protease inhimbitors | ARAD DORIT (US) | 2004-10-07 | — | — | US | disclosed |
| WO-2002076939-A2 | CYSTEINE PROTEASE INHIBITORS | EXEGENICS INC. (US) | 2002-10-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040198716-A1 | Cysteine protease inhimbitors | CTRL, PREP, CLPP | MYC 3220/4885CYP1A2 2215/4885TTR 3447/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.