SCHEMBL251733

SCHEMBL251733

C[C@@H](N)Cc1ccc(C(=O)O)cc1

nearest known ligand 0.62

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 1/20 0.62
ENPEP Q07075 1/20 0.62
TAAR1 Q96RJ0 5/20 0.59
SLC6A2 P23975 4/20 0.59
SLC6A3 Q01959 2/20 0.57
SLC6A4 P31645 2/20 0.57
MAOA P21397 1/20 0.57
SIGMAR1 Q99720 1/20 0.57
CYP2A6 P11509 1/20 0.57
ADORA2A P29274 1/20 0.57
ADORA1 P30542 1/20 0.57
ALDH1A1 P00352 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5183224 1.00 ANPEP (0.62) ANPEPENPEPTAAR1SLC6A2SLC6A3
SCHEMBL2439514 1.00 ANPEP (0.62) ANPEPENPEPTAAR1SLC6A2SLC6A3
Amphetamine SCHEMBL29185448 0.89 TAAR1 (0.70) ANPEPENPEPTAAR1SLC6A2SLC6A3
Amphetamine SCHEMBL21464672 0.89 TAAR1 (0.70) ANPEPENPEPTAAR1SLC6A2SLC6A3
SCHEMBL6539936 0.88 ANPEP (0.51) ANPEPENPEPTAAR1SLC6A2SLC6A3
SCHEMBL9392575 0.84 TAAR1 (0.59) TAAR1SLC6A2SLC6A3SLC6A4MAOA
SCHEMBL6764390 0.84 TAAR1 (0.59) TAAR1SLC6A2SLC6A3SLC6A4MAOA
SCHEMBL8136474 0.84 TAAR1 (0.59) TAAR1SLC6A2SLC6A3SLC6A4MAOA
SCHEMBL8745472 0.84 TAAR1 (0.59) TAAR1SLC6A2SLC6A3SLC6A4MAOA
SCHEMBL1048952 0.84 TAAR1 (0.59) TAAR1SLC6A2SLC6A3SLC6A4MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 529 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118028200-A Acetobacter xylosojae gene engineering bacterium with bcsC knocked out gene, construction method and application thereof 华东师范大学 2024-05-14 CN claimed
CN-116949082-A Reverse screening method of zymomonas mobilis based on pheS gene and application thereof 武汉轻工大学 2023-10-27 CN claimed
CN-113660957-A Compositions, methods, and uses comprising antibody-TLR agonist conjugates AMBRX公司 2021-11-16 CN claimed
CN-110959041-A Methods and compositions for enhancing the production of proteins containing unnatural amino acids AMBRX公司 2020-04-03 CN claimed
WO-2016207626-A1 FLUOROGENIC COMPOUNDS, PROCESS OF PREPARATION THEREOF AND METHODS OF USE THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH (GB) 2016-12-29 WO claimed
CN-104961756-A Preparation method of (S)-Boc-4-dihydroxyborylphenylalanine SHANGHAI INST TECHNOLOGY 2015-10-07 CN claimed
US-20120027706-A1 METHODS FOR TREATING SKIN PIGMENTATION SHAPIRO STANLEY S (US) 2012-02-02 US claimed
US-20080249029-A1 Administering (S)-N-Methyl-D-phenylalanyl-N-[4-[(aminoiminomethyl)aminol-1-(2-benzothiazolylcarbonyl)butyl-L-prolinamide as a protease activated receptor-2 modulator SHAPIRO STANLEY S 2008-10-09 US claimed
US-20030082575-A1 Translation system for use in the generation of protein containing adjusted amino acid sequences THE SCRIPPS RESEARCH INSTITUTE (US) 2003-05-01 US claimed
EP-0656904-A1 PEPTIDE INHIBITORS OF SELECTIN BINDING CENTOCOR INC. (US) 1995-06-14 EP claimed
EP-0584244-A1 PEPTIDE INHIBITORS OF INFLAMMATION THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) 1994-03-02 EP claimed
WO-1993024526-A1 PEPTIDE INHIBITORS OF SELECTIN BINDING CENTOCOR, INC. (US) 1993-12-09 WO claimed
WO-1992020708-A1 PEPTIDE INHIBITORS OF INFLAMMATION BOARD OF REGENTS FOR THE UNIVERSITY OF OKLAHOMA (US) 1992-11-26 WO claimed
EP-4724152-A1 ANTIPERSPIRANT COMPOSITION Unilever IP Holdings B.V. (NL) 2026-04-15 EP disclosed
WO-2025132032-A1 PERSONAL CARE COMPOSITION UNILEVER IP HOLDINGS B.V. (NL) 2025-06-26 WO disclosed
EP-4536173-A1 ANTIPERSPIRANT COMPOSITION Unilever IP Holdings B.V. (NL) 2025-04-16 EP disclosed
US-3975237-A LIGANDS SYVA COMPANY (US) 1976-08-17 US disclosed
US-3966556-A Compounds for enzyme amplification assay methadone analogs SYVA COMPANY (US) 1976-06-29 US disclosed
US-3966764-A ELECTRON SPIN RESONANCE SYVA COMPANY (US) 1976-06-29 US disclosed
US-3966744-A Spin labeled compounds SYVA COMPANY (US) 1976-06-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120027706-A1 METHODS FOR TREATING SKIN PIGMENTATION TYR, MC1R, NQO1 ANPEP 1351/4885ENPEP 382/4885TAAR1 4608/4885
US-20080249029-A1 Administering (S)-N-Methyl-D-phenylalanyl-N-[4-[(aminoiminomethyl)aminol-1-(2-benzothiazolylcarbonyl)butyl-L-prolinamide as a protease activated receptor-2 modulator MC1R, F2RL1, F2R ANPEP 15/4885ENPEP 55/4885TAAR1 1667/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.