SCHEMBL1048952

SCHEMBL1048952

CC(=O)c1ccc(C[C@@H](C)N)cc1

nearest known ligand 0.59

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 5/20 0.59
SLC6A2 P23975 4/20 0.59
KMT2A Q03164 1/20 0.57
SLC6A3 Q01959 2/20 0.53
SLC6A4 P31645 2/20 0.52
MAOA P21397 1/20 0.52
SIGMAR1 Q99720 1/20 0.52
CYP2A6 P11509 1/20 0.52
ADORA2A P29274 1/20 0.52
ADORA1 P30542 1/20 0.52
ACACB O00763 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8136474 1.00 TAAR1 (0.59) TAAR1SLC6A2KMT2ASLC6A3SLC6A4
SCHEMBL17992601 0.87 KMT2A (0.52) TAAR1SLC6A2KMT2AACACB
SCHEMBL6764390 0.84 TAAR1 (0.59) TAAR1SLC6A2SLC6A3SLC6A4MAOA
SCHEMBL251733 0.84 ANPEP (0.62) TAAR1SLC6A2SLC6A3SLC6A4MAOA
SCHEMBL2439514 0.84 ANPEP (0.62) TAAR1SLC6A2SLC6A3SLC6A4MAOA
SCHEMBL8745472 0.84 TAAR1 (0.59) TAAR1SLC6A2SLC6A3SLC6A4MAOA
SCHEMBL18067341 0.84 KMT2A (0.57) KMT2AACACB
SCHEMBL5183224 0.84 ANPEP (0.62) TAAR1SLC6A2SLC6A3SLC6A4MAOA
SCHEMBL9392575 0.84 TAAR1 (0.59) TAAR1SLC6A2SLC6A3SLC6A4MAOA
SCHEMBL585471 0.83 LMNA (0.64) KMT2AACACB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250213502-A1 Amphetamine Controlled Release, Prodrug, and Abuse-deterrent Dosage Forms Pharmapotheca A, Inc. 2025-07-03 US disclosed
US-12208068-B2 Amphetamine controlled release, prodrug, and abuse-deterrent dosage forms Pharmapotheca A Inc. (US) 2025-01-28 US disclosed
US-20230321010-A1 Amphetamine Controlled Release, Prodrug, and Abuse-deterrent Dosage Forms CHEMAPOTHECA, LLC (US) 2023-10-12 US disclosed
US-11717498-B2 Methods of treatment using amphetamine controlled release, prodrug, and abuse deterrent dosage forms Pharmapotheca A, Inc. (US) 2023-08-08 US disclosed
US-11123310-B2 Amphetamine controlled release, prodrug, and abuse-deterrent dosage forms PHARMAPOTHECA, LLC (US) 2021-09-21 US disclosed
US-20210030699-A1 Methods of Treatment Using Amphetamine Controlled Release, Prodrug, and Abuse Deterrent Dosage Forms PHARMAPOTHECA, LLC (US) 2021-02-04 US disclosed
US-20200352883-A1 METHODS OF TREATMENT USING AMPHETAMINE CONTROLLED RELEASE, PRODRUG, AND ABUSE-DETERRENT DOSAGE FORMS CHEMAPOTHECA, LLC (US) 2020-11-12 US disclosed
EP-3478363-A1 AMPHETAMINE CONTROLLED RELEASE, PRODRUG, AND ABUSE DETERRENT DOSAGE FORMS Chemapotheca LLC (US) 2019-05-08 EP disclosed
US-20180243241-A1 AMPHETAMINE CONTROLLED RELEASE, PRODRUG, AND ABUSE-DETERRENT DOSAGE FORMS CHEMAPOTHECA, LLC 2018-08-30 US disclosed
EP-2318126-B1 WATER PURIFICATION MEMBRANES WITH IMPROVED FOULING RESISTANCE UNIV TEXAS (US) 2018-08-22 EP disclosed
EP-2318126-A2 WATER PURIFICATION MEMBRANES WITH IMPROVED FOULING RESISTANCE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2011-05-11 EP disclosed
WO-2011005258-A1 POLYMER DEPOSITION AND MODIFICATION OF MEMBRANES FOR FOULING RESISTANCE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2011-01-13 WO disclosed
US-20100059433-A1 POLYMER DEPOSITION AND MODIFICATION OF MEMBRANES FOR FOULING RESISTANCE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2010-03-11 US disclosed
US-20100051538-A1 WATER PURIFICATION MEMBRANES WITH IMPROVED FOULING RESISTANCE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2010-03-04 US disclosed
WO-2010006196-A2 WATER PURIFICATION MEMBRANES WITH IMPROVED FOULING RESISTANCE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2010-01-14 WO disclosed
EP-1442006-A2 PREPARATION OF AMPHETAMINES FROM PHENYLPROPANOLAMINES Boehringer Ingelheim Chemicals, Inc. (US) 2004-08-04 EP disclosed
WO-2003037843-A2 PREPARATION OF AMPHETAMINES FROM PHENYLPROPANOLAMINES BOEHRINGER INGELHEIM CHEMICALS, INC. (US) 2003-05-08 WO disclosed
US-5166218-A Antilipemic agents or antiglycemic agents HOFFMANN-LA ROCHE INC. (US) 1992-11-24 US disclosed
US-5064863-A Catabolic activity, obesity, diabetes HOFFMANN-LA ROCHE INC. (US) 1991-11-12 US disclosed
EP-0140243-A2 Phenoxypropanol amines F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1985-05-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11123310-B2 Amphetamine controlled release, prodrug, and abuse-deterrent dosage forms SLC6A3, CES2, SLC6A2 TAAR1 52/4885SLC6A2 3/4885KMT2A 1605/4885
US-11717498-B2 Methods of treatment using amphetamine controlled release, prodrug, and abuse deterrent dosage forms SLC6A3, SLC6A2, CES2 TAAR1 51/4885SLC6A2 2/4885KMT2A 1539/4885
US-20200352883-A1 METHODS OF TREATMENT USING AMPHETAMINE CONTROLLED RELEASE, PRODRUG, AND ABUSE-DETERRENT DOSAGE FORMS SLC6A3, SLC6A2, CES2 TAAR1 40/4885SLC6A2 2/4885KMT2A 1492/4885
US-20230321010-A1 Amphetamine Controlled Release, Prodrug, and Abuse-deterrent Dosage Forms SLC6A3, CES2, SLC6A2 TAAR1 37/4885SLC6A2 3/4885KMT2A 1784/4885
US-20210030699-A1 Methods of Treatment Using Amphetamine Controlled Release, Prodrug, and Abuse Deterrent Dosage Forms SLC6A3, SLC6A2, CES2 TAAR1 51/4885SLC6A2 2/4885KMT2A 1539/4885
US-12208068-B2 Amphetamine controlled release, prodrug, and abuse-deterrent dosage forms SLC6A3, CES2, SLC6A2 TAAR1 37/4885SLC6A2 3/4885KMT2A 1784/4885
US-20250213502-A1 Amphetamine Controlled Release, Prodrug, and Abuse-deterrent Dosage Forms SLC6A3, CES2, SLC6A2 TAAR1 52/4885SLC6A2 3/4885KMT2A 1605/4885
US-20180243241-A1 AMPHETAMINE CONTROLLED RELEASE, PRODRUG, AND ABUSE-DETERRENT DOSAGE FORMS SLC6A3, CES2, SLC6A2 TAAR1 52/4885SLC6A2 3/4885KMT2A 1605/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.