Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LPL | P06858 | 1/20 | 0.48 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrogen Peroxide SCHEMBL3918960 | 0.95 | TDP1 (0.57) | TDP1TP53TSHRALDH1A1LPL | |
| Methyl Alcohol SCHEMBL27447590 | 0.92 | TDP1 (0.55) | TDP1TP53ALDH1A1LPLLIPG | |
| Benzene SCHEMBL3223041 | 0.92 | TP53 (0.58) | TDP1TP53ALDH1A1HPGDALOX15 | |
| SCHEMBL11594885 | 0.92 | TP53 (0.58) | TDP1TP53ALDH1A1HPGDALOX15 | |
| SCHEMBL40575 | 0.92 | — | — | |
| Benzene SCHEMBL28308118 | 0.92 | TP53 (0.58) | TDP1TP53ALDH1A1HPGDALOX15 | |
| SCHEMBL9420959 | 0.89 | TP53 (0.55) | TDP1TP53ALDH1A1HPGDALOX15 | |
| Alcohol SCHEMBL351481 | 0.89 | TDP1 (0.65) | TDP1TP53TSHRALDH1A1HPGD | |
| Bromide SCHEMBL7216374 | 0.89 | TP53 (0.55) | TDP1TP53ALDH1A1HPGDALOX15 | |
| Hydrochloric Acid SCHEMBL5792976 | 0.89 | TP53 (0.55) | TDP1TP53ALDH1A1HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103275773-A | High proportion car-used methanol fuel additive | PINGLIANG ZHONGLI NEW ENERGY TECHNOLOGY RES INST | 2013-09-04 | — | — | CN | claimed |
| US-20230142592-A1 | AROMATIC COMPOUND, ORGANIC SEMICONDUCTOR LAYER AND ORGANIC THIN FILM TRANSISTOR | TOSOH CORPORATION (JP) | 2023-05-11 | — | — | US | disclosed |
| CN-104974804-A | Preparation methods of alcohol base liquid fuel and alcohol base liquid fuel additive | SU ZHIYONG | 2015-10-14 | — | — | CN | disclosed |
| CN-103619839-A | Anti-allergic benzocycloheptathiophene derivatives | LIN TONGJUN | 2014-03-05 | — | — | CN | disclosed |
| CN-103275773-A | High proportion car-used methanol fuel additive | PINGLIANG ZHONGLI NEW ENERGY TECHNOLOGY RES INST | 2013-09-04 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230142592-A1 | AROMATIC COMPOUND, ORGANIC SEMICONDUCTOR LAYER AND ORGANIC THIN FILM TRANSISTOR | CHRM1, CHRM2, ACVRL1 | TDP1 2423/4885TP53 3267/4885TSHR 631/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.