Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2513464 | 0.83 | CYP2D6 (0.35) | — | |
| SCHEMBL2517489 | 0.75 | MEN1 (0.37) | MEN1GAAKMT2A | |
| SCHEMBL2880343 | 0.74 | CYP2D6 (0.33) | MEN1GAAKMT2A | |
| SCHEMBL20298105 | 0.73 | CYP2D6 (0.36) | — | |
| SCHEMBL838139 | 0.71 | MEN1 (0.42) | MEN1GAAKMT2A | |
| SCHEMBL2877636 | 0.68 | DUT (0.36) | MEN1GAAKMT2A | |
| SCHEMBL23459342 | 0.68 | — | — | |
| SCHEMBL2517598 | 0.68 | MEN1 (0.35) | MEN1GAAKMT2A | |
| SCHEMBL3757198 | 0.67 | DUT (0.35) | MEN1GAAKMT2A | |
| SCHEMBL2520170 | 0.67 | MEN1 (0.34) | MEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8034938-B2 | Imidazo[4,5-c]quinolines, 6,7,8,9-tetrahydroimidazo[4,5-c]quinolines, imidazo[4,5-c]naphthyridines, and 6,7,8,9-tetrahydroimidazo[4,5-c]naphthyridines) with a CH( R1) group in the fused ring at 1-position of imidazo ring; modulate immune response, by induction of cytokine biosynthesis or other mechanism | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-10-11 | — | — | US | disclosed |