Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.39 |
| ▸ | CNR2 | P34972 | 3/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.31 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.31 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.30 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30059779 | 0.89 | ALOX5 (0.38) | ALOX5CNR2CNR1SCN9A | |
| SCHEMBL25170201 | 0.89 | ALOX5 (0.38) | ALOX5CNR2CNR1SCN9A | |
| SCHEMBL25173436 | 0.87 | AKR1C3 (0.40) | ALOX5CNR2CNR1AKR1C3AKR1C2 | |
| SCHEMBL25170241 | 0.85 | AKR1C3 (0.41) | ALOX5CNR2CNR1AKR1C3AKR1C2 | |
| SCHEMBL25167683 | 0.80 | CNR2 (0.51) | ALOX5CNR2CNR1KCNN4SLC6A3 | |
| SCHEMBL25167681 | 0.79 | NOTUM (0.41) | CNR2CNR1SCN9A | |
| SCHEMBL25460765 | 0.78 | NOTUM (0.44) | ALOX5CNR2CNR1KCNN4SLC6A3 | |
| SCHEMBL25460726 | 0.76 | AKR1C3 (0.40) | AKR1C3AKR1C2CETP | |
| SCHEMBL30057746 | 0.76 | AKR1C3 (0.40) | AKR1C3AKR1C2CETP | |
| SCHEMBL25168983 | 0.76 | AKR1C3 (0.55) | ALOX5AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12281149-B2 | Modulators of G-protein coupled receptors | CARMOT THERAPEUTICS, INC. (US) | 2025-04-22 | — | — | US | disclosed |
| US-20240383960-A1 | Modulators of G-Protein Coupled Receptors | CARMOT THERAPEUTICS INC. (US) | 2024-11-21 | — | — | US | disclosed |
| CN-117980325-A | Modulators of G-protein coupled receptors | 卡莫特治疗学股份有限公司 | 2024-05-03 | — | — | CN | disclosed |
| EP-4337682-A2 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | Carmot Therapeutics Inc. (US) | 2024-03-20 | — | — | EP | disclosed |
| US-20230151074-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | CARMOT THERAPEUTICS, INC. | 2023-05-18 | — | — | US | disclosed |
| US-20230151074-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | CARMOT THERAPEUTICS, INC. | 2023-05-18 | — | — | US | disclosed |
| US-20230151074-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | CARMOT THERAPEUTICS, INC. | 2023-05-18 | — | — | US | disclosed |
| WO-2022241287-A2 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | CARMOT THERAPEUTICS, INC. (US) | 2022-11-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240383960-A1 | Modulators of G-Protein Coupled Receptors | GIPR, GLP1R, GCGR | ALOX5 4292/4885CNR2 204/4885CNR1 131/4885 |
| US-12281149-B2 | Modulators of G-protein coupled receptors | GIPR, GLP1R, GCGR | ALOX5 4324/4885CNR2 217/4885CNR1 125/4885 |
| US-20230151074-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | GIPR, GLP1R, GCGR | ALOX5 4324/4885CNR2 217/4885CNR1 125/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.